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GREM2 Antibody

GREM2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGREM2 Primary Polyclonal Antibody
Also known asGREM2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGREM2
SpecificityThis is a highly specific antibody against GREM2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GREM2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Additionally, All family members are secreted proteins that act as BMP antagonists in embryonic explants and are expressed in the proximal airway epithelium of the lung during embryonic development, Gremlin-1 is required for early limb outgrowth and patterning in the FGF4-SHH feedback loop, The dorsaling factor gremlin belongs to a novel gene family that includes the head-inducing factor Cerberus and the tumor suppressor DAN, secreted gremlin relays the sonic hedgehog signal from the polarizing region to the apical ectodermal ridge, while gremlin-2 binds and blocks the activity of BMP-2 and BMP-4, The gremlin protein family contains antagonists of bone morphogenetic protein (BMP) signaling that are expressed in the neural crest
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CKTSF1B2, Cysteine knot superfamily 1, Cysteine knot superfamily 1 BMP antagonist 2, DAN domain family member 3, DAND 3, DAND3, GREM 2, GREM2_HUMAN, Grem2, Gremlin 2, Gremlin 2 cysteine knot superfamily homolog, Gremlin-2, Gremlin2, PRDC, Protein related to DAN and cerberus, BMP antagonist 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGREM2
Short nameGREM2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namegremlin 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Extracellular, GREM2 and IDBG-107671 and ENSG00000180875 and 64388, Grem2 and IDBG-206362 and ENSMUSG00000050069 and 23893, protein homodimerization activity, this GO :0005125 and cytokine activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0008201 and heparin binding and molecular function this GO :0010172 and embryonic body morphogenesis and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0030514 and negative regulation of BMP signaling pathway and biological process this GO :0036122 and BMP binding and molecular function this GO :0038098 and sequestering of BMP from receptor via BMP binding and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0048263 and determination of dorsal identity and biological process this GO :0060300 and regulation of cytokine activity and biological process, this GO :0005125: cytokine activity, this GO :0005125: cytokine activity and also this GO :0008201: heparin binding and also this GO :0036122: BMP binding and also this GO :0042803: protein homodimerization activity, this GO :0008201: heparin binding, this GO :0036122: BMP binding, this GO :0042803: protein homodimerization activity, gremlin 2
Identity 17655
Gene GREM2
Long gene name DAN family BMP antagonist , gremlin 2
Synonyms gene name cysteine knot superfamily, gremlin 2, homolog (Xenopus laevis) gremlin 2
Synonyms Prdc FLJ21195 CKTSF1B2 DAND3
Synonyms name protein related to DAN and cerberus
Locus 1q43
Discovery year 2004-07-30
GenBank acession AK024848
Entrez gene record 64388
Pubmed identfication 15039429
RefSeq identity NM_022469
Classification DAN family
Havana BLAST/BLAT OTTHUMG00000039909

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