| Long name | GRIK2/GLR6 Primary Polyclonal Antibody |
| Also known as | GRIK2/GLR6 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GRIK2/GLR6 |
| Specificity | This is a highly specific antibody against GRIK2/GLR6 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GRIK2/GLR6 |
| Tested Applications | FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | 2, 3, 4 and one zeta subunit, Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7, The NMDA receptors consist of five subunits: epsilion 1, The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, The zeta subunit is expressed throughout the brainstem, both of which contain glutamate-gated, cation-specific ion channels, neural development and neurodegeneration, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions, whereas the four epsilon subunits display limited distribution, Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DKFZp686H1993, EAA4, Excitatory amino acid receptor 4, G protein coupled receptor family C group 1 member F, GLR 6, GLR6, GLUR 6, GLUR6, GRIK 2, GRIK2, GRIK2 protein, GRIK2_HUMAN, GRM 6, GluR-6, Glutamate receptor, Glutamate receptor 6, Glutamate receptor ionotropic kainate 2, Gprc 1f, Gprc1f, ionotropic kainate 2, CSNB 1B |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GRIK2/GLR6 |
| Short name | GRIK2/GLR6 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | ionotropic, kainate 2/GLR6 (Antibody to), glutamate receptor |
| Alternative technique | antibodies |
| Alternative to gene target | Cell surfaces, EAA4 and GLR6 and GluK2 and GLUK6 and GLUR6 and MRT6, GRIK2 and IDBG-631973 and ENSBTAG00000033153 and 615226, GRIK2 and IDBG-94705 and ENSG00000164418 and 2898, Grik2 and IDBG-149430 and ENSMUSG00000056073 and 14806, glutamatergic and biological process this GO :0042391 and regulation of membrane potential and biological process this GO :0042734 and presynaptic membrane and cellular component this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043025 and neuronal cell body and cellular component this GO :0043113 and receptor clustering and biological process this GO :0043195 and terminal bouton and cellular component this GO :0043204 and perikaryon and cellular component this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0045202 and synapse and cellular component this GO :0045211 and postsynaptic membrane and cellular component this GO :0046328 and regulation of JNK cascade and biological process this GO :0048169 and regulation of long-term neuronal synaptic plasticity and biological process this GO :0048172 and regulation of short-term neuronal synaptic plasticity and biological process this GO :0050804 and regulation of synaptic transmission and biological process this GO :0050806 and positive regulation of synaptic transmission and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0051967 and negative regulation of synaptic transmission, glutamatergic and biological process this GO :0060079 and regulation of excitatory postsynaptic membrane potential and biological process this GO :0060080 and regulation of inhibitory postsynaptic membrane potential and biological process, ionotropic, kainate 2, protein homodimerization activity, this GO :0001662 and behavioral fear response and biological process this GO :0004970 and ionotropic glutamate receptor activity and molecular function this GO :0005215 and transporter activity and molecular function this GO :0005234 and extracellular-glutamate-gated ion channel activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006810 and transport and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006886 and intracellular protein transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007215 and glutamate receptor signaling pathway and biological process this GO :0007268 and synaptic transmission and biological process this GO :0008066 and glutamate receptor activity and molecular function this GO :0008328 and ionotropic glutamate receptor complex and cellular component this GO :0014069 and postsynaptic density and cellular component this GO :0015277 and kainate selective glutamate receptor activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019228 and neuronal action potential and biological process this GO :0030054 and cell junction and cellular component this GO :0030165 and PDZ domain binding and molecular function this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0031624 and ubiquitin conjugating enzyme binding and molecular function this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032839 and dendrite cytoplasm and cellular component this GO :0032983 and kainate selective glutamate receptor complex and cellular component this GO :0034220 and ion transmembrane transport and biological process this GO :0035235 and ionotropic glutamate receptor signaling pathway and biological process this GO :0035249 and synaptic transmission, this GO :0004970: ionotropic glutamate receptor activity, this GO :0004970: ionotropic glutamate receptor activity and also this GO :0005215: transporter activity and also this GO :0005234: extracellular-glutamate-gated ion channel activity and also this GO :0005515: protein binding and also this GO :0008066: glutamate receptor activity and also this GO :0015277: kainate selective glutamate receptor activity and also this GO :0030165: PDZ domain binding and also this GO :0031624: ubiquitin conjugating enzyme binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity, this GO :0005215: transporter activity, this GO :0005234: extracellular-glutamate-gated ion channel activity, this GO :0005515: protein binding, this GO :0008066: glutamate receptor activity, this GO :0015277: kainate selective glutamate receptor activity, this GO :0030165: PDZ domain binding, this GO :0031624: ubiquitin conjugating enzyme binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, glutamate receptor |
| Identity | 4583 |
| Gene | GRIK5 |
| Long gene name | glutamate ionotropic receptor kainate type subunit 5 |
| Synonyms gene | GRIK2 |
| Synonyms gene name | glutamate receptor, ionotropic, kainate 5 |
| Synonyms | GluK5 KA2 |
| Locus | 19q13, 2 |
| Discovery year | 1993-10-21 |
| Entrez gene record | 2901 |
| Pubmed identfication | 7527545 |
| Classification | Glutamate ionotropic receptor kainate type subunits |
| Havana BLAST/BLAT | OTTHUMG00000044573 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue