Name : GRK5 Antibody
Supplier : NJS POLY
Price :406
SKU : GEN5308063125
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | GRK5 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Optimal dilution of the GRK5 antibody should be determined by the researcher |
| Intented use | This GRK5 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P34947 |
| Purity | Antigen affinity |
| Description | It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs), The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation, This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family, G protein-coupled receptor kinase 5 is an enzyme that in humans is encoded by the GRK5 gene |
| Immunogen | Amino acids KREEVDRRVLETEEVYSHKFSEEAKSICKMLLTKDAK of human GRK5 were used as the immunogen for the GRK5 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the GRK5 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization | cytoplasmic, Nuclear |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | GRK5 |
| Short name | GRK5 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | G protein-coupled receptor kinase 5 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | GPRK5, GRK5 and IDBG-640359 and ENSBTAG00000007981 and 281801, GRK5 and IDBG-91131 and ENSG00000198873 and 2869, Grk5 and IDBG-181926 and ENSMUSG00000003228 and 14773, nuclei, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004703 and G-protein coupled receptor kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005080 and protein kinase C binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005543 and phospholipid binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007188 and adenylate cyclase-modulating G-protein coupled receptor signaling pathway and biological process this GO :0007217 and tachykinin receptor signaling pathway and biological process this GO :0008277 and regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004703: G-protein coupled receptor kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005080: protein kinase C binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0005543: phospholipid binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004703: G-protein coupled receptor kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005080: protein kinase C binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0005543: phospholipid binding, this GO :0016772: transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0038032 and termination of G-protein coupled receptor signaling pathway and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0046777 and protein autophosphorylation and biological process, G protein-coupled receptor kinase 5 |
| Identity | 4544 |
| Gene | GRK5 |
| Long gene name | G protein-coupled receptor kinase 5 |
| Synonyms gene | GPRK5 |
| Locus | 10q26, 11 |
| Discovery year | 1994-03-29 |
| GenBank acession | L15388 |
| Entrez gene record | 2869 |
| Pubmed identfication | 7685906 |
| RefSeq identity | NM_005308 |
| Havana BLAST/BLAT | OTTHUMG00000019149 |