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HELT Antibody

HELT Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameHELT Primary Polyclonal Antibody
Also known asHELT PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHELT
SpecificityThis is a highly specific antibody against HELT
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HELT
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Containing a basic helix-loop-helix (bHLH) domain and an Orange domain, HESL (HES-like), HESL exists as two isoforms produced by alternative splicing events, HESL is considered a transcriptional repressor that binds to the canonical E box sequence 5'-CACGCG-3', HESL self-associates and interacts with HES5 and HRT2, The Notch signaling pathway is thought to maintain stem cells through transcriptional activation of HES/HEY family members to repress tissue-specific transcription factors, also known as Mgn or HELT (HES/HEY-like transcription factor), is a 327 amino acid nuclear protein belonging to the HEY family, The Drosophila hairy and Enhancer of split genes encode basic helix-loop-helix (bHLH) transcriptional repressors that function in the Notch signaling pathway and control segmentation and neural development during embryogenesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names HCM1228, HELT, HELT_HUMAN, HES like , HES/HEY like transcription factor, HES/HEY-like transcription factor, HESL, Heslike , Hey like transcription factor, Hey like transcription factor zebrafish, Hey like transcriptional repressor, Megane bHLH factor, Mgn, Hairy and enhancer of split-related protein HELT
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetHELT
Short nameHELT Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHELT (Antibody to)
Alternative techniqueantibodies
Identity 33783
Gene HELT
Long gene name helt bHLH transcription factor
Synonyms gene name Hey-like transcription factor (zebrafish) HES/HEY-like transcription factor
Synonyms HESL HCM1228 Mgn bHLHb44 MEGANE
Synonyms name megane bHLH factor HES-like
Locus 4q35, 1
Discovery year 2008-04-21
GenBank acession BC144567
Entrez gene record 391723
Pubmed identfication 14764602 17611227
RefSeq identity NM_001300781
Classification Basic helix-loop-helix proteins
Havana BLAST/BLAT OTTHUMG00000160484

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