| Long name | FITC Conjugated, HHEX Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | HHEX |
| Specificity | This is a highly specific antibody against HHEX |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human HHEX |
| Gene ID number | 3087 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Establishes anterior identity at two levels, May play a role in hematopoietic differentiation, Transcriptional repressor, acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL, Recognizes the DNA sequence 5'-ATTAA-3' |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | HEX HOX11L-PEN |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | HHEX Conjugated |
| Short name | FITC Conjugated, HHEX Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, hematopoietically expressed homeobox (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DNA binding, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006406 and mRNA export from nucleus and biological process this GO :0007165 and signal transduction and biological process this GO :0007492 and endoderm development and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008190 and eukaryotic initiation factor 4E binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008301 and DNA binding, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048568 and embryonic organ development and biological process this GO :0048729 and tissue morphogenesis and biological process this GO :0048853 and forebrain morphogenesis and biological process this GO :0060431 and primary lung bud formation and biological process this GO :0061009 and common bile duct development and biological process this GO :0061010 and gall bladder development and biological process this GO :0061011 and hepatic duct development and biological process this GO :0061017 and hepatoblast differentiation and biological process this GO :0070365 and hepatocyte differentiation and biological process this GO :0070491 and repressing transcription factor binding and molecular function this GO :0071103 and DNA conformation change and biological process this GO :0071837 and HMG box domain binding and molecular function this GO :0090009 and primitive streak formation and biological process, HEX and HMPH and HOX11L-PEN and PRH and PRHX, HHEX and IDBG-637611 and ENSBTAG00000014217 and 539542, HHEX and IDBG-82541 and ENSG00000152804 and 3087, Hhex and IDBG-161747 and ENSMUSG00000024986 and 15242, bending, bending and also this GO :0017025: TBP-class protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0043565: sequence-specific DNA binding and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0070491: repressing transcription factor binding and also this GO :0071837: HMG box domain binding, bending and molecular function this GO :0009611 and response to wounding and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0010621 and negative regulation of transcription by transcription factor localization and biological process this GO :0010944 and negative regulation of transcription by competitive promoter binding and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0016973 and poly(A)+ mRNA export from nucleus and biological process this GO :0017025 and TBP-class protein binding and molecular function this GO :0022027 and interkinetic nuclear migration and biological process this GO :0030097 and hemopoiesis and biological process this GO :0030154 and cell differentiation and biological process this GO :0030177 and positive regulation of Wnt signaling pathway and biological process this GO :0030183 and B cell differentiation and biological process this GO :0030878 and thyroid gland development and biological process this GO :0030900 and forebrain development and biological process this GO :0030948 and negative regulation of vascular endothelial growth factor receptor signaling pathway and biological process this GO :0031016 and pancreas development and biological process this GO :0032993 and protein-DNA complex and cellular component this GO :0034504 and protein localization to nucleus and biological process this GO :0035050 and embryonic heart tube development and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043434 and response to peptide hormone and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045736 and negative regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0045892 and negative regulation of transcription, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001570 and vasculogenesis and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001889 and liver development and biological process this GO :0002009 and morphogenesis of an epithelium and biological process this GO :0002573 and myeloid leukocyte differentiation and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0008190: eukaryotic initiation factor 4E binding and also this GO :0008301: DNA binding, this GO :0003682: chromatin binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0008190: eukaryotic initiation factor 4E binding, this GO :0008301: DNA binding, this GO :0017025: TBP-class protein binding, this GO :0042803: protein homodimerization activity, this GO :0043565: sequence-specific DNA binding, this GO :0044212: transcription regulatory region DNA binding, this GO :0070491: repressing transcription factor binding, this GO :0071837: HMG box domain binding, hematopoietically expressed homeobox |
| Identity | 4901 |
| Gene | HHEX |
| Long gene name | hematopoietically expressed homeobox |
| Synonyms gene | PRHX |
| Locus | 10q23, 33 |
| Discovery year | 1998-08-04 |
| GenBank acession | Z21533 |
| Entrez gene record | 3087 |
| Pubmed identfication | 8096636 8103988 |
| Classification | NKL subclass homeoboxes and pseudogenes |
| Havana BLAST/BLAT | OTTHUMG00000018762 |
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