Name : HK/Hexokinase 1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN4883431541
| Long name | HK/Hexokinase 1 Primary Polyclonal Antibody |
| Also known as | HK/Hexokinase 1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | HK/Hexokinase 1 |
| Specificity | This is a highly specific antibody against HK/Hexokinase 1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 530-580/917 |
| Subcellular location | Mitochondrion |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Hexokinase 1 |
| Gene ID number | 3098 |
| Swiss Prot | P19367 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Four hexokinase isoenzymes have been identified, Glucokinase is expressed in pancreatic beta cells where it functions as a glucose sensor, Glucokinase lacks the N-terminal hydrophobic cluster, HXK I has been shown to be expressed in brain, HXK II is involved in the uptake and utilization of glucose by adipose and skeletal tissues, HXK III has the highest affinity for glucose, Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids, Of the hexokinases, The hydrophobic cluster is thought to be necessary for membrane binding, This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases, also designated glucokinase or GCK), determining the â, hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, including hexokinase I (HXK I), kidney and heart tissues as well as in hepatoma cell lines, the conversion of glucose to glucose-6-phosphate, &euro, &euro, &oelig, The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, set pointâ, for insulin secretion |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Brain form hexokinase, HK I, HK1, HK1-ta, HK1-tb, HK1-tc, HKI, HMSNR, HXK1, Hexokinase type I, Hexokinase-1, HKD |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | HK/Hexokinase 1 |
| Short name | HK/Hexokinase 1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | HK/Hexokinase 1 (Antibody to) |
| Alternative technique | antibodies |