Name : HLA B27 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN5855015893
| Long name | HLA B27 Primary Polyclonal Antibody |
| Also known as | HLA B27 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | HLA B27 |
| Specificity | This is a highly specific antibody against HLA B27 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HLA B27 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Class I molecules are expressed in nearly all cells and play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum, HLA-B and HLA-C) and class II (HLA-D), HLA-B encodes a membrane anchored heavy chain which hetero-dimerizes with a light chain (â, Human leukocyte antigens (HLAs) are polymorphic members of the MHC family that are specifically involved in the presentation of antigens to the T cell receptor, Polymorphisms yield hundreds of HLA-B alleles, The HLA-B27 allele appears with increased frequency in uveitis patients, The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes, There are two classes of HLA antigens: class I (HLA-A, They are cell-surface receptors that bind peptides and present them to T lymphocytes, &circ, «, -2-Microglobulin) to form MHC-I, Major histocompatibility complex (MHC) molecules form an integral part of the immune response system |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 1B27_HUMAN, HLAB, Leukocyte antigen class I B, Lymphocyte antigen, Major histocompatibility complex class I B, SPDA1, HLA B27 HLA-B27 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | HLA B27 |
| Short name | HLA B27 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Human leukocyte antigen B27 (Antibody to) |
| Alternative technique | antibodies |