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HRD1 Antibody

HRD1 Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenHRD1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the HRD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis HRD1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q86TM6
PurityPurified
Description Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum, HRD1 contains one ring-type zinc finger, HRD1 is expressed in many tissues, Synoviolin/Hrd1 (expressed in rheumatoid synovium) is reported to be a novel causative factor for arthropathy by triggering synovial cell outgrowth through its antiapoptotic effects, kidney and skeletal muscle, liver, pancreas, strongly expressed in brain, HRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress
ImmunogenA portion of amino acids 58-88 from the human protein was used as the immunogen for this HRD1 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the HRD1 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetHRD1
Short nameHRD1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHRD1 (Antibody to)
Alternative techniqueantibodies
Identity 20738
Gene SYVN1
Long gene name synoviolin 1
Synonyms gene name synovial apoptosis inhibitor 1, synoviolin
Synonyms HRD1 DER3
Synonyms name HMG-coA reductase degradation 1 homolog (S, cerevisiae)
Locus 11q13, 1
Discovery year 2004-07-28
GenBank acession AB085847
Entrez gene record 84447
Pubmed identfication 12975321
RefSeq identity NM_032431
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000165607

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