| Long name | Recombinant Human Suppressor of cytokine signaling 1 (SOCS1) |
| Alternative names | JAB, JAK binding protein, JAK-binding protein, JAK-binding protein, SSI-1, STAT induced SH3 protein 1, STAT-induced STAT inhibitor 1, STAT-induced STAT inhibitor 1, Suppressor of cytokine signaling 1, TIP-3, TIP-3, Tec-interacting protein 3, Tec-interacting protein 3, cytokine-inducible SH2 protein 1, suppressor of cytokine signaling 1, suppressor of cytokine signaling 1, suppressor of cytokine signaling 1 |
| Gene name | SOCS1 |
| Other gene names | CIS1, CISH1, JAB, JAB, SOCS-1, SOCS-1, SOCS1, SSI-1, SSI-1, SSI1, SSI1, TIP-3, TIP3, TIP3, SOCS1 |
| General description | All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, Suppressor of cytokine signaling 1(SOCS1) is a recombinant protein expressed in Baculovirus |
| Product category | Recombinant Proteins |
| Expression system | Baculovirus |
| Available also expressed in: | Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity | Greater than 90% (determined by SDS-PAGE) |
| Form | Lyophilized protein |
| Storage | Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications | IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Description | HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in , Kinase, breast cancer tumor, Cytokines and Chemokines are chemotaxis related small proteins between 5 to 20 kDa, biological pathways |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target | Suppressor of cytokine signaling 1 (SOCS1) |
| Short name | Suppressor of cytokine signaling 1 (SOCS1) |
| Species | Humans, Human |
| Alternative name | sapiens Suppressor on cytokine signaling 1 (suppressor on cytokine signaling 1), H |
| Alternative to gene target | CIS1 and CISH1 and JAB and SOCS-1 and SSI-1 and SSI1 and TIP3, SOCS1 and IDBG-14621 and ENSG00000185338 and 8651, SOCS1 and IDBG-648701 and ENSBTAG00000004386 and 518795, Socs1 and IDBG-132667 and ENSMUSG00000038037 and 12703, nuclei, protein kinase binding, this GO :0001932 and regulation of protein phosphorylation and biological process this GO :0004860 and protein kinase inhibitor activity and molecular function this GO :0005159 and insulin-like growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0019210 and kinase inhibitor activity and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0040008 and regulation of growth and biological process this GO :0042518 and negative regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0045087 and innate immune response and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0046426 and negative regulation of JAK-STAT cascade and biological process this GO :0046627 and negative regulation of insulin receptor signaling pathway and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060334 and regulation of interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060338 and regulation of type I interferon-mediated signaling pathway and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0071230 and cellular response to amino acid stimulus and biological process, this GO :0004860: protein kinase inhibitor activity, this GO :0004860: protein kinase inhibitor activity and also this GO :0005159: insulin-like growth factor receptor binding and also this GO :0005515: protein binding and also this GO :0019210: kinase inhibitor activity and also this GO :0019901: protein kinase binding, this GO :0005159: insulin-like growth factor receptor binding, this GO :0005515: protein binding, this GO :0019210: kinase inhibitor activity, this GO :0019901: protein kinase binding, suppressor of cytokine signaling 1 |
| Identity | 19383 |
| Gene | SOCS1 |
| Long gene name | suppressor of cytokine signaling 1 |
| Synonyms | SOCS-1 SSI-1 JAB TIP3 Cish1 |
| Locus | 16p13, 13 |
| Discovery year | 2002-11-13 |
| GenBank acession | U88326 |
| Pubmed identfication | 7796808 9266833 |
| Classification | Suppressors of cytokine signaling SH2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000129792 |
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