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ICOS Antibody

ICOS Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration09% sodium azide, 4 with 0, In 1X PBS pH 7
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenICOS
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IHC, WB
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the ICOS antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis ICOS antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9Y6W8
PurityPurified
Description It forms homodimers and plays an important role in cell-cell signaling, and regulation of cell proliferation, immune responses, ICOS belongs to the CD28 and CTLA-4 cell-surface receptor family
ImmunogenA portion of amino acids 156-185 from the human protein was used as the immunogen for this ICOS antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ICOS antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetICOS
Short nameICOS Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameinducible T-cell co-stimulator (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Extracellular, ICOS and IDBG-643378 and ENSBTAG00000021596 and 507026, ICOS and IDBG-79246 and ENSG00000163600 and 29851, Icos and IDBG-159737 and ENSMUSG00000026009 and 54167, protein binding, this GO :0002517 and T cell tolerance induction and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0031295 and T cell costimulation and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, inducible T-cell co-stimulator
Identity 5351
Gene ICOS
Long gene name inducible T-cell costimulator
Synonyms AILIM CD278
Synonyms name activation-inducible lymphocyte immunomediatory molecule
Locus 2q33, 2
Discovery year 2000-02-29
GenBank acession AB023135
Entrez gene record 29851
Pubmed identfication 9930702 10617205
RefSeq identity NM_012092
Classification CD molecules
Havana BLAST/BLAT OTTHUMG00000132880
Locus Specific Databases ICOSbase: Mutation registry for ICOS deficiency LRG_65

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