| Long name | 3, 6) Monoclonal Antibody, IGF2 (519CT14 |
| Also known as | 3, 6) Monoclonal Antibody, IGF2 (519CT14 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | IGF2 |
| Specificity | This is a highly specific antibody against IGF2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 3, 519CT14, 6 |
| Source | This IGF2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from human IGF2 |
| Gene ID number | 3481 |
| Swiss Prot | P01344 |
| Tested Applications | WB |
| Recommended dilutions | WB(1:100~500) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3, IGF-II is influenced by placental lactogen and may play a role in fetal development, In vitro, Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion, they are potent mitogens for cultured cells, The insulin-like growth factors possess growth-promoting activity |
| Purification method | This antibody is prepared by Euglobin precipitation followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | C11orf43, IGF-II, IGF2, Insulin-like growth factor II, PP1446, PP9974, Somatomedin-A, T3M-11-derived growth factor, GRDF |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 3, 6) Monoclonal, IGF2 (519CT14 |
| Short name | 3, 6) Monoclonal Antibody, IGF2 (519CT14 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 3, 6) monoclonal (Antibody to), insulin-like growth factor 2 (somatomedin A) (519CT14 |
| Alternative technique | antibodies |
| Alternative to gene target | C11orf43 and IGF-II and PP9974, DNA-templated and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007565 and female pregnancy and biological process this GO :0007596 and blood coagulation and biological process this GO :0007613 and memory and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0009314 and response to radiation and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0030168 and platelet activation and biological process this GO :0030546 and receptor activator activity and molecular function this GO :0031017 and exocrine pancreas development and biological process this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0031667 and response to nutrient levels and biological process this GO :0032355 and response to estradiol and biological process this GO :0035094 and response to nicotine and biological process this GO :0038028 and insulin receptor signaling pathway via phosphatidylinositol 3-kinase and biological process this GO :0042060 and wound healing and biological process this GO :0042104 and positive regulation of activated T cell proliferation and biological process this GO :0042493 and response to drug and biological process this GO :0043085 and positive regulation of catalytic activity and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043539 and protein serine/threonine kinase activator activity and molecular function this GO :0044267 and cellular protein metabolic process and biological process this GO :0045471 and response to ethanol and biological process this GO :0045725 and positive regulation of glycogen biosynthetic process and biological process this GO :0045840 and positive regulation of mitosis and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046628 and positive regulation of insulin receptor signaling pathway and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0051146 and striated muscle cell differentiation and biological process this GO :0051781 and positive regulation of cell division and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071902 and positive regulation of protein serine/threonine kinase activity and biological process this GO :0090031 and positive regulation of steroid hormone biosynthetic process and biological process this GO :2000273 and positive regulation of receptor activity and biological process this GO :2000467 and positive regulation of glycogen (starch) synthase activity and biological process, Extracellular, IGF2 and IDBG-20829 and ENSG00000167244 and 3481, IGF2 and IDBG-645244 and ENSBTAG00000013066 and 281240, Igf2 and IDBG-212623 and ENSMUSG00000048583 and 16002, protein serine/threonine kinase activator activity, this GO :0001501 and skeletal system development and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002576 and platelet degranulation and biological process this GO :0005158 and insulin receptor binding and molecular function this GO :0005159 and insulin-like growth factor receptor binding and molecular function this GO :0005179 and hormone activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006006 and glucose metabolic process and biological process this GO :0006349 and regulation of gene expression by genetic imprinting and biological process this GO :0006355 and regulation of transcription, this GO :0005158: insulin receptor binding, this GO :0005158: insulin receptor binding and also this GO :0005159: insulin-like growth factor receptor binding and also this GO :0005179: hormone activity and also this GO :0005515: protein binding and also this GO :0008083: growth factor activity and also this GO :0030546: receptor activator activity and also this GO :0043539: protein serine/threonine kinase activator activity, this GO :0005159: insulin-like growth factor receptor binding, this GO :0005179: hormone activity, this GO :0005515: protein binding, this GO :0008083: growth factor activity, this GO :0030546: receptor activator activity, this GO :0043539: protein serine/threonine kinase activator activity, insulin-like growth factor 2 (somatomedin A) |
| Identity | 5466 |
| Gene | IGF2 |
| Long gene name | insulin like growth factor 2 |
| Synonyms gene | C11orf43 |
| Synonyms gene name | chromosome 11 open reading frame 43 insulin-like growth factor 2 |
| Synonyms | FLJ44734 IGF-II |
| Synonyms name | somatomedin A preptin |
| Locus | 11p15, 5 |
| Discovery year | 2001-06-22 |
| GenBank acession | M29645 AK025719 |
| Entrez gene record | 3481 |
| Pubmed identfication | 2450353 3167054 |
| RefSeq identity | NM_000612 |
| Havana BLAST/BLAT | OTTHUMG00000009395 |
| Locus Specific Databases | LOVD - Leiden Open Variation Database LRG_1031 |
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