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IGHM Antibody

IGHM Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration09% sodium azide, 4 with 0, In 1X PBS pH 7
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenIGHM
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC, WB
Recommended dilutionsIHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the IGHM antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis IGHM antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P01871
PurityPurified
Description After the antigen binds to the B-cell receptor, It is also found in soluble form, It may cause death of cells by apoptosis, Membrane-bound IgM induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases, The membrane-bound form is found in the majority of normal B-cells alongside with IgD, They have been shown to be involved in early recognition of external invaders like bacteria and viruses, [UniProt], as well as in recognition and elimination of precancerous and cancerous lesions, cellular waste and modified self, the secreted form is secreted in large amounts, which represents about 30% of the total serum immunoglobulins where it is found almost exclusively as a homopentamer, IgM antibodies play an important role in primary defense mechanisms
ImmunogenA portion of amino acids 103-131 from the human protein was used as the immunogen for this IGHM antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the IGHM antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetIGHM
Short nameIGHM Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameimmunoglobulin heavy constant mu (Antibody to)
Alternative techniqueantibodies
Alternative to gene target IDBG-636218 and IDBG-636218 and ENSBTAG00000048049 and, IGHM and IDBG-124400 and ENSG00000211899 and 102725284, Ighm and IDBG-222557 and ENSMUSG00000076617 and, multiple, protein binding, this GO :0005515 and protein binding and molecular function, this GO :0005515: protein binding, this GO :0005515: protein binding, immunoglobulin heavy constant mu
Identity 11752
Gene TFE3
Long gene name transcription factor binding to IGHM enhancer 3
Synonyms TFEA bHLHe33
Synonyms name transcription factor E family member A
Locus Xp11, 23
Discovery year 1990-10-16
GenBank acession X96717
Entrez gene record 7030
Pubmed identfication 1672758 1685140
RefSeq identity NM_006521
Classification Basic helix-loop-helix proteins
Havana BLAST/BLAT OTTHUMG00000022690
Locus Specific Databases Mental Retardation database

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