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IL5RA/CD125 Antibody

IL5RA/CD125 Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long nameIL5RA/CD125 Primary Polyclonal Antibody
Also known asIL5RA/CD125 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenIL5RA/CD125
SpecificityThis is a highly specific antibody against IL5RA/CD125
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IL-5R alpha
Gene ID number3568
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Six alternatively spliced transcript variants encoding three distinct isoforms have been reported, The beta subunit is activated by the ligand binding, The binding of this protein to IL5 depends on the beta subunit, The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), This protein has been found to interact with syndecan binding protein (syntenin), and interleukin 5(IL5), and is required for the biological activities of IL5, colony stimulating factor 2 (CSF2/GM-CSF), which is required for IL5 mediated activation of the transcription factor SOX4, The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CD125 antigen, CDw125, HSIL5R3, IL-5R, IL-5R alpha, IL5R, IL5RA, IL5RA_HUMAN, Interleukin 5 Receptor alpha, Interleukin 5 receptor subunit alpha, MGC26560, interleukin 5 receptor type 3, Interleukin-5 receptor alpha
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetIL5RA/CD125
Short nameIL5RA/CD125 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name alpha/CD125 (Antibody to), interleukin 5 receptor
Alternative techniqueantibodies
Alternative to gene target CD125 and CDw125 and HSIL5R3 and IL5R, Extracellular, IL5RA and IDBG-13590 and ENSG00000091181 and 3568, IL5RA and IDBG-644842 and ENSBTAG00000000273 and 615848, Il5ra and IDBG-173890 and ENSMUSG00000005364 and 16192, alpha, protein binding, this GO :0002437 and inflammatory response to antigenic stimulus and biological process this GO :0004896 and cytokine receptor activity and molecular function this GO :0004914 and interleukin-5 receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0032674 and regulation of interleukin-5 production and biological process this GO :0038043 and interleukin-5-mediated signaling pathway and biological process this GO :0071310 and cellular response to organic substance and biological process, this GO :0004896: cytokine receptor activity, this GO :0004896: cytokine receptor activity and also this GO :0004914: interleukin-5 receptor activity and also this GO :0005515: protein binding, this GO :0004914: interleukin-5 receptor activity, this GO :0005515: protein binding, interleukin 5 receptor
Identity 6017
Gene IL5RA
Long gene name interleukin 5 receptor subunit alpha
Synonyms gene IL5R
Synonyms gene name alpha , interleukin 5 receptor
Synonyms CDw125 CD125
Locus 3p26, 2
Discovery year 1992-06-18
GenBank acession M96652
Entrez gene record 3568
Pubmed identfication 1732409
Classification CD molecules Interleukin receptors
Havana BLAST/BLAT OTTHUMG00000090245

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