| Alternative name1 | FLJ35968, Insulin Protease), Insulin-degrading Enzyme, Insulinase, insulin-degrading enzyme, Anti-Insulysin (IDE |
| Alternative name2 | FLJ35968, Insulin Protease), Insulin-degrading Enzyme, Insulinase, insulin-degrading enzyme, Insulysin (IDE |
| Alternative name3 | FLJ35968, Insulin Protease), Insulin-degrading Enzyme, Insulinase, insulin-degrading enzyme, Insulysin (IDE |
| Alternative name4 | Insulysin |
| Alternative name5 | FLJ35968, Insulin Protease), Insulin-degrading Enzyme, Insulinase, insulin-degrading enzyme, Anti -Insulysin (IDE |
| Other names | N/A, N/A, N/A, insulysin, insulysin |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | N/A, N/A, N/A, CMU_002640 |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | IgG |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Goat |
| Species reactivity | Human |
| Specificity and cross-reactivity | Species sequence homology: canine, Recognizes human Insulysin at ~120kD |
| Purification method | Affinity Purified by affinity chromatography |
| Form/Appearance | 0, 0, pH 7, 02% sodium azide, 3, 5% BSA, Supplied as a liquid in Tris |
| Concentration | N/A |
| Storage and shipping | Aliquots are stable for at least 12 monthsproductone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for: | Western Blot (WB), ELISA (EL/EIA) |
| Description | Activating enzymes will cut off the domain that is biological active to become functional, If the substrate is DNA they are called restriction enzymes, Enzymes are cleaving the substrate |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target | Insulin-degrading Insulin Protease), Insulinase, insulin-degrading FLJ35968, Insulysin (IDE |
| Short name | FLJ35968, Insulin Protease), Insulin-degrading Enzyme, Insulinase, insulin-degrading enzyme, Insulysin (IDE |
| Technique | enzymes, Enzyme |
| Alternative name | FLJ35968, Insulin Protease), Insulin-degrading Enzyme, Insulinase, insulin-degrading enzyme, Insulysin (insulin-degrading enzyme |
| Alternative technique | enzymes |
| Alternative to gene target | IDE and IDBG-637578 and ENSBTAG00000019759 and 523752, IDE and IDBG-82456 and ENSG00000119912 and 3416, INSULYSIN, Ide and IDBG-161417 and ENSMUSG00000056999 and 15925, metal ion binding, nuclei, this GO :0001540 and beta-amyloid binding and molecular function this GO :0001948 and glycoprotein binding and molecular function this GO :0003824 and catalytic activity and molecular function this GO :0004222 and metalloendopeptidase activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005777 and peroxisome and cellular component this GO :0005782 and peroxisomal matrix and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006508 and proteolysis and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008340 and determination of adult lifespan and biological process this GO :0009986 and cell surface and cellular component this GO :0010815 and bradykinin catabolic process and biological process this GO :0010992 and ubiquitin homeostasis and biological process this GO :0016032 and viral process and biological process this GO :0016887 and ATPase activity and molecular function this GO :0017046 and peptide hormone binding and molecular function this GO :0031597 and cytosolic proteasome complex and cellular component this GO :0031626 and beta-endorphin binding and molecular function this GO :0032461 and positive regulation of protein oli this GO merization and biological process this GO :0042277 and peptide binding and molecular function this GO :0042447 and hormone catabolic process and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043130 and ubiquitin binding and molecular function this GO :0043559 and insulin binding and molecular function this GO :0044257 and cellular protein catabolic process and biological process this GO :0045861 and negative regulation of proteolysis and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050435 and beta-amyloid metabolic process and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051289 and protein homotetramerization and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051603 and proteolysis involved in cellular protein catabolic process and biological process this GO :1901142 and insulin metabolic process and biological process this GO :1901143 and insulin catabolic process and biological process, this GO :0001540: beta-amyloid binding, this GO :0001540: beta-amyloid binding and also this GO :0001948: glycoprotein binding and also this GO :0003824: catalytic activity and also this GO :0004222: metalloendopeptidase activity and also this GO :0005102: receptor binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008270: zinc ion binding and also this GO :0016887: ATPase activity and also this GO :0017046: peptide hormone binding and also this GO :0031626: beta-endorphin binding and also this GO :0042277: peptide binding and also this GO :0042803: protein homodimerization activity and also this GO :0043130: ubiquitin binding and also this GO :0043559: insulin binding and also this GO :0046872: metal ion binding, this GO :0001948: glycoprotein binding, this GO :0003824: catalytic activity, this GO :0004222: metalloendopeptidase activity, this GO :0005102: receptor binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0008270: zinc ion binding, this GO :0016887: ATPase activity, this GO :0017046: peptide hormone binding, this GO :0031626: beta-endorphin binding, this GO :0042277: peptide binding, this GO :0042803: protein homodimerization activity, this GO :0043130: ubiquitin binding, this GO :0043559: insulin binding, this GO :0046872: metal ion binding, insulin-degrading enzyme |
| Identity | 5381 |
| Gene | IDE |
| Long gene name | insulin degrading enzyme |
| Synonyms gene name | insulin-degrading enzyme |
| Synonyms name | insulysin |
| Locus | 10q23, 33 |
| Discovery year | 1990-07-03 |
| GenBank acession | M21188 |
| Entrez gene record | 3416 |
| Pubmed identfication | 2293021 |
| RefSeq identity | NM_004969 |
| Havana BLAST/BLAT | OTTHUMG00000018759 |
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