Name : Integrin alpha 7 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2144810362
| Long name | Integrin alpha 7 Primary Polyclonal Antibody |
| Also known as | Integrin alpha 7 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Integrin alpha 7/ITGA7 |
| Specificity | This is a highly specific antibody against Integrin alpha 7/ITGA7 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 730-780/1181 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Integrin alpha 7 |
| Gene ID number | 3679 |
| Swiss Prot | Q13683 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Acts as Schwann cell receptor for laminin-2, Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity), During myogenic differentiation, Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells, and facilitate their localization at laminin-rich sites of secondary fiber formation, but isoform Alpha-7X1B is less active on laminin 1 (In vitro), it may induce changes in the shape and mobility of myoblasts, viability and functional integrity, Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ITGA7, UNQ46/PRO768, Integrin alpha-7 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Integrin alpha 7 |
| Short name | Integrin alpha 7 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Integrin a 7 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6143 |
| Gene | ITGA7 |
| Long gene name | integrin subunit alpha 7 |
| Synonyms gene name | alpha 7 , integrin |
| Locus | 12q13, 2 |
| Discovery year | 1992-02-27 |
| Entrez gene record | 3679 |
| Pubmed identfication | 7607681 |
| RefSeq identity | NM_002206 |
| Classification | Integrin alpha subunits |
| Havana BLAST/BLAT | OTTHUMG00000170699 |
| Locus Specific Databases | LRG_871 |