Name : Integrin alpha E Antibody
Supplier : NJS POLY
Price :389
SKU : GEN4891500023
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Integrin alpha E |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Titration of the Integrin alpha E antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This Integrin alpha E antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P38570 |
| Purity | Antigen affinity |
| Description | ITGAE is expressed widely on intraepithelial lymphocyte (IEL) T cells (both alphabeta T cells and gammadelta T cells) and on some peripheral regulatory T cells (Tregs), ITGAE shares overall homology with other alpha integrins but has a unique 55-amino acid extra region located just N-terminal to the I domain that contains 18 consecutive charged residues and a proteolytic cleavage site, also known as CD103, is a protein that in human is encoded by the ITGAE gene, which is important for decreasing the immune response and appears to play a crucial role in the prevention of autoimmune diseases, ITGAE (Integrin alpha E) |
| Immunogen | An amino acid sequence from the C-terminus of human Integrin alpha E (KRKYQQLNLESIRKAQ) was used as the immunogen for this Integrin alpha E antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Integrin alpha E antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Integrin alpha E |
| Short name | Integrin alpha E Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Integrin a E (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6147 |
| Gene | ITGAE |
| Long gene name | integrin subunit alpha E |
| Synonyms gene name | alpha E (antigen CD103, alpha polypeptide) , human mucosal lymphocyte antigen 1, integrin |
| Synonyms | CD103 HUMINAE |
| Synonyms name | alpha polypeptide , antigen CD103 human mucosal lymphocyte antigen 1 |
| Locus | 17p13, 2 |
| Discovery year | 1997-06-09 |
| GenBank acession | L25851 |
| Entrez gene record | 3682 |
| Pubmed identfication | 8119947 |
| RefSeq identity | NM_002208 |
| Classification | Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000177634 |