Name : IP10 Antibody / CXCL10
Supplier : NJS POLY
Price :406
SKU : GEN8990813381
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | IP10 / CXCL10 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, WB |
| Recommended dilutions | 1-0, 1-0, 5ug/ml, 5ug/ml, ELISA : 0, Western blot: 0 |
| Notes | Optimal dilution of the CXCL10 antibody should be determined by the researcher |
| Intented use | This CXCL10 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P02778 |
| Purity | Antigen affinity |
| Description | (1987) reported the isolation of an interferon-inducible gene that encodes a 98-amino acid protein called IP10, CXCL10), CXCR3, IP10 inhibits bone marrow colony formation, It is a small cytokine belonging to the CXC chemokine family, Luster et al, The chemokine IFN-gamma-inducible protein 10 (IP-10, The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines, a CXC chemokine, also known as Interferon gamma-induced protein 10kDa (IP-10) or small-inducible cytokine B10, and its receptor, and promotes T cell adhesion to endothelial cells, has antitumor activity in vivo, is a chemoattractant for human monocytes and T cells, is a protein that in humans is encoded by the CXCL10 gene, were found to be overexpressed in lymph node cells of EAMG rats, C-X-C motif chemokine 10 (CXCL10) |
| Immunogen | Amino acids 22-98 of human IP10/CXCL10 were used as the immunogen for the CXCL10 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CXCL10 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | IP10 / CXCL10 |
| Short name | IP10 Antibody / CXCL10 |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | IP10 (Antibody to) / chemokine (C-X-C motif) ligand 10 |
| Alternative technique | antibodies |
| Alternative to gene target | C7 and crg-2 and gIP-10 and IFI10 and INP10 and IP-10 and mob-1 and SCYB10, CXCL10 and IDBG-25212 and ENSG00000169245 and 3627, CXCL10 and IDBG-643109 and ENSBTAG00000001725 and 615107, CXCR3 chemokine receptor binding, Cxcl10 and IDBG-179916 and ENSMUSG00000034855 and 15945, Extracellular, this GO :0002690 and positive regulation of leukocyte chemotaxis and biological process this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007517 and muscle organ development and biological process this GO :0008009 and chemokine activity and molecular function this GO :0008015 and blood circulation and biological process this GO :0008201 and heparin binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008603 and cAMP-dependent protein kinase regulator activity and molecular function this GO :0009306 and protein secretion and biological process this GO :0009409 and response to cold and biological process this GO :0009615 and response to virus and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0010332 and response to gamma radiation and biological process this GO :0010818 and T cell chemotaxis and biological process this GO :0010996 and response to auditory stimulus and biological process this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030816 and positive regulation of cAMP metabolic process and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0033280 and response to vitamin D and biological process this GO :0034605 and cellular response to heat and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0043950 and positive regulation of cAMP-mediated signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0045859 and regulation of protein kinase activity and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048248 and CXCR3 chemokine receptor binding and molecular function this GO :0051281 and positive regulation of release of sequestered calcium ion into cytosol and biological process this GO :0051607 and defense response to virus and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :2000406 and positive regulation of T cell migration and biological process, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005515: protein binding and also this GO :0008009: chemokine activity and also this GO :0008201: heparin binding and also this GO :0008603: cAMP-dependent protein kinase regulator activity and also this GO :0048248: CXCR3 chemokine receptor binding, this GO :0005515: protein binding, this GO :0008009: chemokine activity, this GO :0008201: heparin binding, this GO :0008603: cAMP-dependent protein kinase regulator activity, this GO :0048248: CXCR3 chemokine receptor binding, chemokine (C-X-C motif) ligand 10 |
| Identity | 10637 |
| Gene | CXCL10 |
| Long gene name | C-X-C motif chemokine ligand 10 |
| Synonyms gene | INP10 SCYB10 |
| Synonyms gene name | member 10 chemokine (C-X-C motif) ligand 10 , small inducible cytokine subfamily B (Cys-X-Cys) |
| Synonyms | IFI10 IP-10 crg-2 mob-1 C7 gIP-10 |
| Locus | 4q21, 1 |
| Discovery year | 1999-12-09 |
| GenBank acession | X02530 |
| Entrez gene record | 3627 |
| Pubmed identfication | 2437586 3925348 |
| Classification | Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT | OTTHUMG00000160887 |