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IRF8 Antibody

IRF8 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenIRF8
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB, FACS
Recommended dilutionsFlow Cytometry: 1:10-1:50, Western blot: 1:1000
NotesTitration of the IRF8 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis IRF8 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q02556
PurityPurified
Description IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection, Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain, The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta, Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family
ImmunogenA portion of amino acids 384-409 from the human protein was used as the immunogen for this IRF8 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the IRF8 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetIRF8
Short nameIRF8 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameinterferon regulatory factor 8 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006909 and pha this GO cytosis and biological process this GO :0006955 and immune response and biological process this GO :0009617 and response to bacterium and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030099 and myeloid cell differentiation and biological process this GO :0032729 and positive regulation of interferon-gamma production and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0042832 and defense response to protozoan and biological process this GO :0044130 and negative regulation of growth of symbiont in host and biological process this GO :0045087 and innate immune response and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0060261 and positive regulation of transcription initiation from RNA polymerase II promoter and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process, H-ICSBP and ICSBP and ICSBP1 and IMD32A and IMD32B and IRF-8, IRF8 and IDBG-45278 and ENSG00000140968 and 3394, IRF8 and IDBG-630167 and ENSBTAG00000017824 and 614909, Irf8 and IDBG-196509 and ENSMUSG00000041515 and 15900, nuclei, protein binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000975 and regulatory region DNA binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0006355 and regulation of transcription, this GO :0000975: regulatory region DNA binding, this GO :0000975: regulatory region DNA binding and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003705: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding, this GO :0003677: DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003705: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, interferon regulatory factor 8
Identity 5358
Gene IRF8
Long gene name interferon regulatory factor 8
Synonyms gene ICSBP1
Synonyms gene name interferon consensus sequence binding protein 1
Synonyms IRF-8 ICSBP
Locus 16q24, 1
Discovery year 1993-09-09
GenBank acession M91196
Entrez gene record 3394
Pubmed identfication 1460054 11997525
RefSeq identity NM_002163
Havana BLAST/BLAT OTTHUMG00000137648
Locus Specific Databases LRG_294

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