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IRS-2 Antibody, FITC Conjugated

IRS-2 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, IRS-2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenIRS-2
SpecificityThis is a highly specific antibody against IRS-2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range540-590/1338
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human IRS-2
Gene ID number8660
Swiss ProtQ9Y4H2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Each IRS is believed to have different functions, Four members of the IRS family have been described, Summary: This gene encodes the insulin receptor substrate 2, The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, a cytoplasmic signaling molecule that mediates effects of insulin, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment, however, insulin-like growth factor 1, the distinct physiological roles of each IRS are unclear, The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms IRS2, Insulin receptor substrate 2, IRS-2
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetIRS-2 Conjugated
Short name FITC Conjugated, IRS-2 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, IRS-2 (Antibody to)
Alternative techniqueantibodies

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