| Long name | ITPR3 Primary Polyclonal Antibody |
| Also known as | ITPR3 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ITPR3 |
| Specificity | This is a highly specific antibody against ITPR3 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ITPR3 |
| Gene ID number | 3710 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | IP3R, IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, IP3R-II and IP3R-III, Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), The inositol 1, Three IP3 receptor subtypes have been described and are designated IP3R-I, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types, but is also expressed at high levels in the liver, growth factors and neurotransmitters, which convert phosphatidylinositol-4, 4, 4, 5 bisphosphate into IP3 and diacylglycerol (DAG), 5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, 5-triphosphate receptor, Inositol 1 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 4 antibody 5-trisphosphate receptor, 5-trisphosphate receptor type 3, FLJ36205, IP3 receptor, IP3 receptor isoform 3, IP3R, IP3R 3, IP3R3, ITPR 3, ITPR3, ITPR3_HUMAN, Inositol 1, Inositol 1, Type 3 InsP3 receptor, Type 3 inositol 1, Type 3 inositol 1, 4, 4, 5 trisphosphate receptor, 5 trisphosphate receptor type 3, IP3R-III |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ITPR3 |
| Short name | ITPR3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | classification 3 (Antibody to), 4, 5-trisphosphate receptor, inositol 1 |
| Alternative technique | antibodies |
| Alternative to gene target | IP3R and IP3R3, ITPR3 and IDBG-629118 and ENSBTAG00000013245 and 281879, ITPR3 and IDBG-82972 and ENSG00000096433 and 3710, Itpr3 and IDBG-156294 and ENSMUSG00000042644 and 16440, inositol 1, nuclei, this GO :0000822 and inositol hexakisphosphate binding and molecular function this GO :0005216 and ion channel activity and molecular function this GO :0005218 and intracellular ligand-gated calcium channel activity and molecular function this GO :0005220 and inositol 1, this GO :0000822: inositol hexakisphosphate binding, this GO :0000822: inositol hexakisphosphate binding and also this GO :0005216: ion channel activity and also this GO :0005218: intracellular ligand-gated calcium channel activity and also this GO :0005220: inositol 1, this GO :0005216: ion channel activity, this GO :0005218: intracellular ligand-gated calcium channel activity, this GO :0005220: inositol 1, this GO :0005262: calcium channel activity, this GO :0005488: binding, this GO :0005515: protein binding, this GO :0035091: phosphatidylinositol binding, this GO :0043533: inositol 1, this GO :0070679: inositol 1, type 3, 3, 3, 3, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 5 tetrakisphosphate binding, 5 tetrakisphosphate binding and also this GO :0070679: inositol 1, 5 tetrakisphosphate binding and molecular function this GO :0044281 and small molecule metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045177 and apical part of cell and cellular component this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0050796 and regulation of insulin secretion and biological process this GO :0050913 and sensory perception of bitter taste and biological process this GO :0050916 and sensory perception of sweet taste and biological process this GO :0050917 and sensory perception of umami taste and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051592 and response to calcium ion and biological process this GO :0055085 and transmembrane transport and biological process this GO :0060291 and long-term synaptic potentiation and biological process this GO :0060402 and calcium ion transport into cytosol and biological process this GO :0070588 and calcium ion transmembrane transport and biological process this GO :0070679 and inositol 1, 5 trisphosphate binding, 5 trisphosphate binding, 5 trisphosphate binding and molecular function, 5-trisphosphate receptor, 5-trisphosphate-sensitive calcium-release channel activity, 5-trisphosphate-sensitive calcium-release channel activity and also this GO :0005262: calcium channel activity and also this GO :0005488: binding and also this GO :0005515: protein binding and also this GO :0035091: phosphatidylinositol binding and also this GO :0043533: inositol 1, 5-trisphosphate-sensitive calcium-release channel activity and molecular function this GO :0005262 and calcium channel activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005640 and nuclear outer membrane and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005903 and brush border and cellular component this GO :0006112 and energy reserve metabolic process and biological process this GO :0006811 and ion transport and biological process this GO :0006816 and calcium ion transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007202 and activation of phospholipase C activity and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007596 and blood coagulation and biological process this GO :0007613 and memory and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0016020 and membrane and cellular component this GO :0030168 and platelet activation and biological process this GO :0031095 and platelet dense tubular network membrane and cellular component this GO :0035091 and phosphatidylinositol binding and molecular function this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043209 and myelin sheath and cellular component this GO :0043235 and receptor complex and cellular component this GO :0043533 and inositol 1, inositol 1 |
| Identity | 6182 |
| Gene | ITPR3 |
| Long gene name | inositol 1, 4, 5-trisphosphate receptor type 3 |
| Synonyms gene name | inositol 1, type 3 , type 3 inositol 1, 4, 4, 5-triphosphate receptor, 5-trisphosphate receptor |
| Synonyms | IP3R3 |
| Locus | 6p21, 31 |
| Discovery year | 1991-06-05 |
| GenBank acession | D26351 |
| Entrez gene record | 3710 |
| Pubmed identfication | 8081734 8288584 |
| RefSeq identity | NM_002224 |
| Classification | Inositol 1, 4, 5-triphosphate receptors Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT | OTTHUMG00000014532 |
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