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Jarid1C Antibody, ALEXA FLUOR 488

Jarid1C Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, Jarid1C Polyclonal Antibody
Also known asAnti-Jarid1C PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenJarid1C
SpecificityThis is a highly specific antibody against Jarid1C
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Jarid1C/KDM5C
Gene ID Number11184
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4', Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20', MRXSJ is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period, MRXSJ patients manifest mental retardation associated with variable features such as slowly progressive spastic paraplegia, Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements, facial dysmorphism, seizures, thereby playing a central role in histone code, Histone demethylase that specifically demethylates 'Lys-4' of histone H3, Involvement in disease:Defects in KDM5C are the cause of mental retardation syndromic X-linked JARID1C-related (MRXSJ) , Tissue specificity:br>
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms DXS1272E XE169
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Jarid1C Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetJarid1C
Short nameJarid1C Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Jarid1C (Antibody to)
Alternative techniqueantibodies
Identity 11114
Gene KDM5C
Long gene name lysine demethylase 5C
Synonyms gene SMCX JARID1C MRX13
Synonyms gene name AT rich interactive domain 1C (RBP2-like) Smcy homolog, AT rich interactive domain 1C mental retardation, Jumonji, X-linked (mouse) jumonji, X-linked 13 lysine (K)-specific demethylase 5C
Locus Xp11, 22
Discovery year 1999-04-23
GenBank acession Z29650
Entrez gene record 8242
Pubmed identfication 7951230 8162017 19826449
RefSeq identity NM_004187
Classification X-linked mental retardation PHD finger proteins Lysine demethylases AT-rich interaction domain containing
Havana BLAST/BLAT OTTHUMG00000021606
Locus Specific Databases KDM5C database at LOVD

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