Name : JMJD2A Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN1873238782
| Long name | JMJD2A Primary Polyclonal Antibody |
| Also known as | JMJD2A PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | JMJD2A |
| Specificity | This is a highly specific antibody against JMJD2A |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human JMJD2A/KDM4A |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, Demethylation of Lys residue generates formaldehyde and succinate, Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20', Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively, thereby playing a central role in histone code, while it has no activity on mono- and dimethylated residues, Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | JMJD2, JmjC domain containing histone demethylation protein 3A, JmjC domain-containing histone demethylation protein 3A, Jumonji domain containing 2, Jumonji domain containing 2A, Jumonji domain containing protein 2A, Jumonji domain-containing protein 2A, KDM2A_HUMAN, KDM4A, KIAA0677, Lysine-specic demethylase 4A, jumonji C domain containing histone demethylase 3A, JMJ2A |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | JMJD2A |
| Short name | JMJD2A Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | JMJD2A (Antibody to) |
| Alternative technique | antibodies |
| Identity | 22978 |
| Gene | KDM4A |
| Long gene name | lysine demethylase 4A |
| Synonyms gene | JMJD2 JMJD2A |
| Synonyms gene name | jumonji domain containing 2 jumonji domain containing 2A lysine (K)-specific demethylase 4A |
| Synonyms | KIAA0677 JHDM3A TDRD14A |
| Synonyms name | jumonji C domain-containing histone demethylase 3A tudor domain containing 14A |
| Locus | 1p34, 1 , 2-p34 |
| Discovery year | 2003-08-08 |
| GenBank acession | AB014577 |
| Entrez gene record | 9682 |
| Pubmed identfication | 9734811 15138608 |
| RefSeq identity | NM_014663 |
| Classification | Lysine demethylases Tudor domain containing |
| Havana BLAST/BLAT | OTTHUMG00000007560 |