JMY Antibody

JMY Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 263

Size 0.1ml

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Long name	JMY Primary Polyclonal Antibody
Also known as	JMY PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	JMY
Specificity	This is a highly specific antibody against JMY
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen range	445-475/988
Subcellular location	Nucleus, Cytoplasm
Source	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human JMY
Gene ID number	133746
Swiss Prot	Q8N9B5
Tested Applications	IF(IHC-P), IHC-P
Recommended dilutions	IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity	Mouse, Rat, Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Activates the Arp2/3 complex to induce branched actin filament networks, Also catalyzes actin polymerization in the absence of Arp2/3, Contributes to cell motility by controlling actin dynamics, In cytoplasm, In nucleus, Increases p53/TP53-dependent transcription and apoptosis, May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments, The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location (By similarity), acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300, acts as a nucleation-promoting factor for both branched and unbranched actin filaments, creating unbranched filaments, suggesting an important role in p53/TP53 stress response such as DNA damage, Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	JMY, Junction-mediating and -regulatory protein, WHDC1L3, WHAMM2
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target	JMY
Short name	JMY Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	p53 cofactor (Antibody to), junction mediating and regulatory protein
Alternative technique	antibodies
Alternative to gene target	JMY and IDBG-30979 and ENSG00000152409 and 133746, JMY and IDBG-645239 and ENSBTAG00000025856 and 101909783, Jmy and IDBG-172833 and ENSMUSG00000021690 and 57748, nuclei, p53 cofactor, protein binding, this GO :0003713 and transcription coactivator activity and molecular function this GO :0003779 and actin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006281 and DNA repair and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0031252 and cell leading edge and cellular component this GO :0034314 and Arp2/3 complex-mediated actin nucleation and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0070060 and 'de novo' actin filament nucleation and biological process this GO :0070358 and actin polymerization-dependent cell motility and biological process this GO :0072332 and intrinsic apoptotic signaling pathway by p53 class mediator and biological process, this GO :0003713: transcription coactivator activity, this GO :0003713: transcription coactivator activity and also this GO :0003779: actin binding and also this GO :0005515: protein binding, this GO :0003779: actin binding, this GO :0005515: protein binding, 528498, junction mediating and regulatory protein
Identity	28916
Gene	JMY
Long gene name	junction mediating and regulatory protein, p53 cofactor
Synonyms	FLJ37870 WHAMM2
Locus	5q14, 1
Discovery year	2009-02-06
GenBank acession	AK095189
Entrez gene record	133746
Pubmed identfication	10518217 22316129
RefSeq identity	NM_152405
Classification	Wiskott-Aldrich Syndrome protein family
Havana BLAST/BLAT	OTTHUMG00000131301

JMY Antibody

JMY Antibody size: 0.1ml 263

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