Name : KCNQ1 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3418124865
| Long name | ALEXA FLUOR 647 Conjugated, KCNQ1 Polyclonal Antibody |
| Also known as | Anti-KCNQ1 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | KCNQ1 |
| Specificity | This is a highly specific antibody against KCNQ1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 500-550/676 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KCNQ-1 |
| Gene ID Number | 3784 |
| Swiss Prot | P51787 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Dog, Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current, Elicits a rapidly activating, May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors, potassium-selective outward current, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea, Probably important in cardiac repolarization |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | Kv7, 1 KCNA8 KVLQT1 JLNS1 LQT1 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the KCNQ1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | KCNQ1 |
| Short name | KCNQ1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, KCNQ1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6294 |
| Gene | KCNQ1 |
| Long gene name | potassium voltage-gated channel subfamily Q member 1 |
| Synonyms gene | LQT KCNA9 |
| Synonyms gene name | KQT-like subfamily, member 1 , member 1 potassium channel, potassium voltage-gated channel, voltage gated KQT-like subfamily Q |
| Synonyms name | Jervell and Lange-Nielsen syndrome 1 |
| Locus | 11p15, 4 , 5-p15 |
| Discovery year | 1997-02-05 |
| GenBank acession | AF000571 |
| Entrez gene record | 3784 |
| Pubmed identfication | 8528244 16382104 |
| RefSeq identity | NM_000218 |
| Classification | Potassium voltage-gated channels |
| Havana BLAST/BLAT | OTTHUMG00000009900 |
| Locus Specific Databases | Gene Connection for the Heart KCNQ1 database at LOVD-China CCHMC-BMI &, UC Hearing Loss Mutation Database LRG_287 |