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KEAP1 Antibody

KEAP1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameKEAP1 Primary Polyclonal Antibody
Also known asKEAP1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenKEAP1
SpecificityThis is a highly specific antibody against KEAP1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range75-125/624
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KEAP1
Gene ID number9817
Swiss ProtQ14145
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol, Targets PGAM5 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression, Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Cytosolic inhibitor of Nrf2, KEAP1, KIAA0132, KLHL19, Kelch-like ECH-associated protein 1, Kelch-like protein 19, INrf2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetKEAP1
Short nameKEAP1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameKEAP1 (Antibody to)
Alternative techniqueantibodies
Identity 23177
Gene KEAP1
Long gene name kelch like ECH associated protein 1
Synonyms KIAA0132 MGC10630 MGC1114 MGC20887 MGC4407 MGC9454 INrf2 KLHL19
Synonyms name kelch-like family member 19
Locus 19p13, 2
Discovery year 2003-09-30
GenBank acession AF361886
Entrez gene record 9817
RefSeq identity NM_012289
Classification BTB domain containing Kelch like
Havana BLAST/BLAT OTTHUMG00000180579

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