Name : KIBRA Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN3719790530
| Long name | KIBRA Primary Polyclonal Antibody |
| Also known as | KIBRA PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | KIBRA |
| Specificity | This is a highly specific antibody against KIBRA |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 370-420/1113 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KIBRA |
| Gene ID number | 23286 |
| Swiss Prot | Q8IX03 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Acts as a substrate for PRKCZ, Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation, Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, Modulates directional migration of podocytes, Plays a role in cognition and memory performance, Regulates collagen-stimulated activation of the ERK/MAPK cascade, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis, Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | HBEBP3, HBEBP36, HBeAg-binding protein 3, KIAA0869, Kidney and brain protein, MEMRYQTL, PPP1R168, Protein KIBRA, WW domain-containing protein 1, WWC1, KIBRA |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | KIBRA |
| Short name | KIBRA Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | KIBRA (Antibody to) |
| Alternative technique | antibodies |
| Identity | 29435 |
| Gene | WWC1 |
| Long gene name | WW and C2 domain containing 1 |
| Synonyms gene name | C2 and coiled-coil domain containing 1 , WW |
| Synonyms | KIBRA KIAA0869 PPP1R168 |
| Synonyms name | protein phosphatase 1, regulatory subunit 168 |
| Locus | 5q34 |
| Discovery year | 2006-02-22 |
| GenBank acession | AF506799 |
| Entrez gene record | 23286 |
| Pubmed identfication | 10048485 12559952 |
| RefSeq identity | NM_015238 |
| Classification | Protein phosphatase 1 regulatory subunits C2 and WW domain containing |
| Havana BLAST/BLAT | OTTHUMG00000130408 |