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KLF1, 2, 4 Antibody, FITC Conjugated

KLF1, 2, 4 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name 2, 4 Polyclonal Antibody, FITC Conjugated, KLF1
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target Antigen 2, 4, KLF1
Specificity 2, 4, This is a highly specific antibody against KLF1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range279-303/362
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human KLF1
Gene ID number10661
Swiss ProtQ13351
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Able to activate CD44 and AQP1 promoters, Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene, Furthermore, Is a dual regulator of fetal-to-adult globin switching, This dual activity ensures that, When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation (By similarity), fetal hemoglobin levels are low, in most adults, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes, Transcription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms EKLF
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target 2, 4 Conjugated, KLF1
Short name 2, 4 Antibody, FITC Conjugated, KLF1
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name 2, 4 (Antibody to), fluorecein coupled, Kruppel-like factor 1 (erythroid)
Alternative techniqueantibodies
Alternative to gene target CDAN4 and EKLF and HBFQTL6 and INLU, DNA-templated and biological process this GO :0030218 and erythrocyte differentiation and biological process this GO :0035162 and embryonic hemopoiesis and biological process this GO :0043249 and erythrocyte maturation and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048821 and erythrocyte development and biological process this GO :1901653 and cellular response to peptide and biological process, KLF1 and IDBG-31252 and ENSG00000105610 and 10661, KLF1 and IDBG-642908 and ENSBTAG00000006083 and 784295, Klf1 and IDBG-175231 and ENSMUSG00000054191 and 16596, metal ion binding, nuclei, this GO :0000790 and nuclear chromatin and cellular component this GO :0000987 and core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001701 and in utero embryonic development and biological process this GO :0001889 and liver development and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0006338 and chromatin remodeling and biological process this GO :0006351 and transcription, this GO :0000987: core promoter proximal region sequence-specific DNA binding, this GO :0000987: core promoter proximal region sequence-specific DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0046872: metal ion binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0044212: transcription regulatory region DNA binding, this GO :0046872: metal ion binding, Kruppel-like factor 1 (erythroid)
Identity 6345
Gene KLF1
Long gene name Kruppel like factor 1
Synonyms gene name Kruppel-like factor 1 (erythroid)
Synonyms name erythroid Kruppel-like factor
Locus 19p13, 13
Discovery year 1999-12-14
GenBank acession U37106
Entrez gene record 10661
Pubmed identfication 8924208 9119377
RefSeq identity NM_006563
Classification Kruppel like factors Zinc fingers C2H2-type
Havana BLAST/BLAT OTTHUMG00000180536
Locus Specific Databases LRG_825

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