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Klotho Antibody

Klotho Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameKlotho Primary Polyclonal Antibody
Also known asKlotho PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenKlotho
SpecificityThis is a highly specific antibody against Klotho
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range400-450/1012
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Klotho
Gene ID number9365
Swiss ProtQ9UEF7
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity), However, May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity), The Klotho peptide generated by cleavage of the membrane-bound isoform may be an anti-aging circulating hormone which would extend life span by inhibiting insulin/IGF1 signaling, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo, May have weak glycosidase activity towards glucuronylated steroids
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names KL, Klotho
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetKlotho
Short nameKlotho Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameKlotho (Antibody to)
Alternative techniqueantibodies
Identity 6344
Gene KL
Long gene name klotho
Locus 13q13, 1
Discovery year 1999-03-24
GenBank acession AB005142
Entrez gene record 9365
Pubmed identfication 9464267
Havana BLAST/BLAT OTTHUMG00000017408
Locus Specific Databases The Globin Gene Server

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