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Lamin B Receptor Antibody

Lamin B Receptor Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameLamin B Receptor Primary Polyclonal Antibody
Also known asLamin B Receptor PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenLamin B Receptor
SpecificityThis is a highly specific antibody against Lamin B Receptor
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range20-70/615
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Lamin B Receptor
Gene ID number3930
Swiss ProtQ14739
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin, It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures, Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane, The cleavage of lamins results in nuclear disregulation and cell death, such as DNA replication and chromatin organization, Lamins are nuclear membrane proteins that serve to maintain specific cellular functions
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DHCR14B, Integral nuclear envelope inner membrane protein, LBR, LMN2R, Lamin-B receptor, TDRD18, PHA
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetLamin B Receptor
Short nameLamin B Receptor Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameLamin B Receptor (Antibody to)
Alternative techniqueantibodies
Identity 6518
Gene LBR
Long gene name lamin B receptor
Synonyms DHCR14B TDRD18
Synonyms name tudor domain containing 18
Locus 1q42, 12
Discovery year 1995-04-27
GenBank acession L25931
Entrez gene record 3930
Pubmed identfication 8157663 9878250
RefSeq identity NM_002296
Classification Tudor domain containing
Havana BLAST/BLAT OTTHUMG00000037520

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