Name : Lamin B2 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN5309596453
| Long name | ALEXA FLUOR 594 Conjugated, Lamin B2 Polyclonal Antibody |
| Also known as | Anti-Lamin B2 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Lamin B2 |
| Specificity | This is a highly specific antibody against Lamin B2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Lamin B2 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | B-type lamins undergo a series of modifications, Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations, Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family, Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, This family, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity, structure and substrate specificity from any previously described protease family, such as farnesylation and phosphorylation, termed CED-3/ICE, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin, A unique family of Cysteine proteases has been described that differs in sequence |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | Lamin B2 |
| Short name | Lamin B2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, Lamin B2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6638 |
| Gene | LMNB2 |
| Long gene name | lamin B2 |
| Synonyms gene | LMN2 |
| Locus | 19p13, 3 |
| Discovery year | 1992-04-09 |
| GenBank acession | M94362 |
| Entrez gene record | 84823 |
| Pubmed identfication | 1630457 |
| RefSeq identity | NM_032737 |
| Classification | Lamins |
| Havana BLAST/BLAT | OTTHUMG00000150626 |