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Lamin B2 Antibody, ALEXA FLUOR 594

Lamin B2 Antibody, ALEXA FLUOR 594 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 594 Conjugated, Lamin B2 Polyclonal Antibody
Also known asAnti-Lamin B2 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLamin B2
SpecificityThis is a highly specific antibody against Lamin B2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Lamin B2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen B-type lamins undergo a series of modifications, Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations, Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family, Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, This family, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity, structure and substrate specificity from any previously described protease family, such as farnesylation and phosphorylation, termed CED-3/ICE, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin, A unique family of Cysteine proteases has been described that differs in sequence
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetLamin B2
Short nameLamin B2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, Lamin B2 (Antibody to)
Alternative techniqueantibodies
Identity 6638
Gene LMNB2
Long gene name lamin B2
Synonyms gene LMN2
Locus 19p13, 3
Discovery year 1992-04-09
GenBank acession M94362
Entrez gene record 84823
Pubmed identfication 1630457
RefSeq identity NM_032737
Classification Lamins
Havana BLAST/BLAT OTTHUMG00000150626

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