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LASP1 Antibody

LASP1 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenLASP1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ICC, IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0
Notes Titration of the LASP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis LASP1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q14847
PurityAntigen affinity
Description In most of these cancers, LASP1 and ERBB2 were simultaneously overexpressed, LASP1 has been shown to interact with Zyxin, Northern blot analysis revealed that LASP1 mRNA was expressed at a basal level in all normal tissues examined and overexpressed in 8% of primary breast cancers, This gene encodes a member of a LIM protein subfamily which is characterized by a LIM motif and a domain of Src homology region 3, This protein functions as an actin-binding protein and possibly in cytoskeletal organization, LIM and SH3 domain protein 1 is a protein that in humans is encoded by the LASP1 gene
ImmunogenAmino acids 16-30 (EKVNCLDKFWHKACF-human) were used as the immunogen for this LASP1 antibody (100% rat homology)
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the LASP1 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetLASP1
Short nameLASP1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameLASP1 (Antibody to)
Alternative techniqueantibodies
Identity 6513
Gene LASP1
Long gene name LIM and SH3 protein 1
Synonyms MLN50 Lasp-1
Locus 17q12
Discovery year 1997-05-22
Entrez gene record 3927
Pubmed identfication 7490069 25622104
RefSeq identity NM_006148
Classification LIM domain containing
Havana BLAST/BLAT OTTHUMG00000133182

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