Name : LDB1/CLIM-2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN1183712664
| Long name | LDB1/CLIM-2 Primary Polyclonal Antibody |
| Also known as | LDB1/CLIM-2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | LDB1/CLIM-2 |
| Specificity | This is a highly specific antibody against LDB1/CLIM-2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LDB1/CLIM-2 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | LMO1 and LMO2, LMO1 and LMO2 are expressed in the adult CNS in a cell type-specific manner, LMO2 and the related protein LMO4 are expressed in thymic precursor cells, LMO2 lacks a specific DNA-binding homeobox domain but rather assembles into transcriptional regulatory complexes to mediate gene expression by interacting with the widely expressed nuclear LIM interactor (NLI), LMO4 is also expressed in mature T cells, NLI, The LIM domain consists of a cysteine-rich zinc-binding motif that is present in a variety of transcription factors, and Schwann cell progenitors, and the related protein CLIM-2, are nuclear factors that are characterized by a conserved LIM domain, cranial neural crest cells, dorsal limb bud mesenchyme, facilitate the formation of heteromeric LIM complexes and also enhance the nuclear retention of LIM proteins, including the LIM homeobox (LHX) proteins expressed in the central nervous system and involved in cell differentiation, known also as CLIM-1, motor neurons, somite, where they are differentially regulated by neuronal activity and are involved in regulating the cellular differentiated phenotype of neurons, The LIM-only (LMO) proteins |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CLIM 2, CLIM-2, Carboxyl-terminal LIM domain-binding protein 2, LDB-1, LDB1_HUMAN, LIM Domain Binding 1, LIM domain binding factor CLIM2, LIM domain-binding factor CLIM2, LIM domain-binding protein 1, NLI, Nuclear LIM Domain Interactor, Nuclear LIM interactor antibodyxldb1, hLdb1, ldb1, Carboxyl Terminal LIM Domain Binding 2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | LDB1/CLIM-2 |
| Short name | LDB1/CLIM-2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | LDB1/CLIM-2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6532 |
| Gene | LDB1 |
| Long gene name | LIM domain binding 1 |
| Synonyms | NLI CLIM2 |
| Synonyms name | carboxy terminal LIM domain protein 2 |
| Locus | 10q24, 32 |
| Discovery year | 1999-01-22 |
| GenBank acession | AF068652 |
| Entrez gene record | 8861 |
| Pubmed identfication | 9503020 9799849 |
| RefSeq identity | NM_001113407 |
| Havana BLAST/BLAT | OTTHUMG00000018950 |