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LILRB2 Antibody

LILRB2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameLILRB2 Primary Polyclonal Antibody
Also known asLILRB2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenLILRB2
SpecificityThis is a highly specific antibody against LILRB2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LILRB2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen B cells, ILT-4, MIR-10 or CD85D antigen, These receptors all contain a cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM), When they bind to MHC (or other ligands) and ITIM is tyrosine phosphorylated, also designated LIR-2, competes with CD8A for binding to class I MHC antigens, dendritic cells, have an inhibitory function and are type I membrane proteins, lung and liver, natural killer (NK) cells, peripheral blood leukocytes and tissues such as placenta, protein-tyrosine phosphatases are recruited and an inhibitory signal cascade triggered, Leukocyte immunoglobulin-like receptors (LIRs) are members of the immunoglobulin superfamily of glycoproteins and are predominantly expressed by monocytes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CD85 antigen-like family member D, CD85d, CD85d antigen, ILT 4, ILT-4, ILT4, Immunoglobulin like transcript 4, Immunoglobulin-like transcript 4, LILRA6, LILRB2, LIR 2, LIR-2, LIR2, LIRB2_HUMAN, LIRb, Leukocyte immunoglobulin like receptor 2, Leukocyte immunoglobulin like receptor subfamily B member 2, Leukocyte immunoglobulin-like receptor, Leukocyte immunoglobulin-like receptor 2, Leukocyte immunoglobulin-like receptor subfamily B member 2, MIR 10, MIR-10, MIR10, Monocyte/macrophage immunoglobulin like receptor 10, Monocyte/macrophage immunoglobulin-like receptor 10, member 2, subfamily B with TM and ITIM domains, CD85D
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetLILRB2
Short nameLILRB2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name member 2 (Antibody to), subfamily B (including TM and ITIM domains), leukocyte immunoglobulin-like receptor
Alternative techniqueantibodies
Alternative to gene target CD85D and ILT-4 and ILT4 and LIR-2 and LIR2 and MIR-10 and MIR10, Extracellular, LILRB2 and IDBG-68447 and ENSG00000131042 and 10288, cell adhesion molecule binding, member 2, subfamily B (with TM and ITIM domains), this GO :0002578 and negative regulation of antigen processing and presentation and biological process this GO :0002666 and positive regulation of T cell tolerance induction and biological process this GO :0002767 and immune response-inhibiting cell surface receptor signaling pathway and biological process this GO :0002774 and Fc receptor mediated inhibitory signaling pathway and biological process this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0006968 and cellular defense response and biological process this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008157 and protein phosphatase 1 binding and molecular function this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0023029 and MHC class Ib protein binding and molecular function this GO :0032396 and inhibitory MHC class I receptor activity and molecular function this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0034113 and heterotypic cell-cell adhesion and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042130 and negative regulation of T cell proliferation and biological process this GO :0042288 and MHC class I protein binding and molecular function this GO :0045591 and positive regulation of regulatory T cell differentiation and biological process this GO :0050776 and regulation of immune response and biological process this GO :0050839 and cell adhesion molecule binding and molecular function this GO :0051926 and negative regulation of calcium ion transport and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :2001198 and regulation of dendritic cell differentiation and biological process, this GO :0004872: receptor activity, this GO :0004872: receptor activity and also this GO :0005515: protein binding and also this GO :0008157: protein phosphatase 1 binding and also this GO :0023029: MHC class Ib protein binding and also this GO :0032396: inhibitory MHC class I receptor activity and also this GO :0042288: MHC class I protein binding and also this GO :0050839: cell adhesion molecule binding, this GO :0005515: protein binding, this GO :0008157: protein phosphatase 1 binding, this GO :0023029: MHC class Ib protein binding, this GO :0032396: inhibitory MHC class I receptor activity, this GO :0042288: MHC class I protein binding, this GO :0050839: cell adhesion molecule binding, leukocyte immunoglobulin-like receptor
Identity 6606
Gene LILRB2
Long gene name leukocyte immunoglobulin like receptor B2
Synonyms gene name leukocyte immunoglobulin-like receptor, member 2 , subfamily B (with TM and ITIM domains)
Synonyms LIR-2 ILT4 MIR-10 LIR2 CD85d MIR10
Synonyms name myeloid inhibitory receptor 10 leucocyte Ig-like receptor B2
Locus 19q13, 4
Discovery year 2000-01-11
GenBank acession AF000574
Pubmed identfication 9151699 9079806
Classification Inhibitory leukocyte immunoglobulin like receptors CD molecules
Havana BLAST/BLAT OTTHUMG00000064896

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