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LIN28B Antibody

LIN28B Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenLIN28B
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IHC, WB, IF
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:100, Western blot: 1:1000
NotesTitration of the LIN28B antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis LIN28B antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q6ZN17
PurityPurified
Description A short LIN28B isoform was also identified in non-tumor liver tissue and fetal liver, Although predominantly localized in the cytoplasm, Induced expression of exogenous LIN28B in a tet-off cell line promoted cancer cell proliferation, LIN28B conserves a cold shock domain and a pair of CCHC zinc finger domains, LIN28B protein shows cell cycle-dependent nuclear translocation in Huh7 cells, Overexpression of LIN28B was noted in most HCC cell lines and clinical samples, Phylogenetic analysis suggests that they might arise as a result of duplication from an ancestral gene, Similar with lin-28 proteins, The heterochronic gene lin-28 is a key regulator of developmental timing in the nematode Caenorhabditis elegans, Lin-28 homolog B (LIN28B) is overexpressed in hepatocellular carcinoma
ImmunogenA portion of amino acids 1-30 from the human protein was used as the immunogen for this LIN28B antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the LIN28B antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetLIN28B
Short nameLIN28B Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameLIN28B (Antibody to)
Alternative techniqueantibodies
Identity 32207
Gene LIN28B
Long gene name lin-28 homolog B
Synonyms gene name elegans) , lin-28 homolog B (C
Synonyms FLJ16517 CSDD2
Locus 6q16, 3-q21
Discovery year 2005-08-22
GenBank acession AK131411
Entrez gene record 389421
RefSeq identity NM_001004317
Havana BLAST/BLAT OTTHUMG00000015290

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