| Alternative name1 | ILS, Isolated Lissencephaly Sequence), MDCR, MDS, Miller-Dieker Syndrome, Miller-Dieker Syndrome, PAFAH1B1, SBH, SCLH, Subcortical Band Heterotopia, Subcortical Laminar Heterotopia, Anti-Lissencephaly-1 (LIS-1 |
| Alternative name2 | ILS, Isolated Lissencephaly Sequence), MDCR, MDS, Miller-Dieker Syndrome, Miller-Dieker Syndrome, PAFAH1B1, SBH, SCLH, Subcortical Band Heterotopia, Subcortical Laminar Heterotopia, Lissencephaly-1 (LIS-1 |
| Alternative name3 | ILS, Isolated Lissencephaly Sequence), MDCR, MDS, Miller-Dieker Syndrome, Miller-Dieker Syndrome, PAFAH1B1, SBH, SCLH, Subcortical Band Heterotopia, Subcortical Laminar Heterotopia, Lissencephaly-1 (LIS-1 |
| Alternative name4 | Lissencephaly-1 |
| Alternative name5 | ILS, Isolated Lissencephaly Sequence), MDCR, MDS, Miller-Dieker Syndrome, Miller-Dieker Syndrome, PAFAH1B1, SBH, SCLH, Subcortical Band Heterotopia, Subcortical Laminar Heterotopia, Anti -Lissencephaly-1 (LIS-1 |
| Other names | CG8440 gene product from transcript CG8440-RE, CG8440-PA, CG8440-PB, CG8440-PC, CG8440-PD, CG8440-PE, CG8440-PF, Lis-1-PA, Lis-1-PB, Lis-1-PC, Lis-1-PD, Lis-1-PE, Lis-1-PF, Lissencephaly-1, Lissencephaly-1, Lissencephaly-1, Lissencephaly-1, Lissencephaly-1, Lissencephaly-1, Lissencephaly-1, Lissencephaly-1 homolog, N/A, Paf-AHbeta, isoform A, isoform B, isoform C, isoform D, isoform E, isoform F, isoform F, lissencephaly-1, platelet-activating factor acetylhydrolase Ib beta-subunit homolog, Lissencephaly-1 |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | CG8440, D-Lis1, DLIS-1, DLIS1, DLis-1, DLis1, Dlis-1, Dlis1, DmLIS1, DmelCG8440, LIS-1, Lis 1, Lis-1, Lis1, Lis1, dLis1, l(2)k13209, l(2R)W8, lis-1, lis1, n(2)k11702, Lis-1 |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | IgG |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Goat |
| Species reactivity | Mouse, Human |
| Specificity and cross-reactivity | Expected to crossreact with Human due to sequence homology, Recognizes mouse Lissencephaly-1 |
| Purification method | Affinity Purified from goat serum by ammonium sulfate precipitation followed by immunoaffinity chromatography |
| Form/Appearance | 0, 0, pH 7, 02% sodium azide, 3, 5% BSA, Supplied as a liquid in TBS |
| Concentration | N/A |
| Storage and shipping | Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Freeze productone should be stored at -20 degrees Celsius, Further dilutions can be made in assay buffer, aliquot and add glycerol (40-50%), centrifuge the original vial after thawing and prior to removing the cap, Store at 4 degrees Celsius for short term storage |
| Tested for: | Western Blot (WB) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target | ILS, Isolated Lissencephaly, MDCR, MDS, Miller-Dieker Syndrome, Miller-Dieker Syndrome, PAFAH1B1, SBH, SCLH, Subcortical Band Heterotopia, Subcortical Laminar Heterotopia, Lissencephaly-1 (LIS-1 |
| Short name | ILS, Isolated Lissencephaly Sequence), MDCR, MDS, Miller-Dieker Syndrome, Miller-Dieker Syndrome, PAFAH1B1, SBH, SCLH, Subcortical Band Heterotopia, Subcortical Laminar Heterotopia, Lissencephaly-1 (LIS-1 |
| Alternative name | ILS, Isolated Lissencephaly Sequence), MDCR, MDS, Miller-Dieker Syndrome, Miller-Dieker Syndrome, SBH, SCLH, Subcortical Band Heterotopia, Subcortical Laminar Heterotopia, platelet-activating factor acetylhydrolase 1b, regulatory functionnal sequence 1 (45kDa), Lissencephaly-1 (LIS-1 |
| Alternative to gene target | LIS1 and LIS2 and MDCR and MDS and PAFAH, PAFAH1B1 and IDBG-16417 and ENSG00000007168 and 5048, PAFAH1B1 and IDBG-633101 and ENSBTAG00000016806 and 282513, Pafah1b1 and IDBG-198862 and ENSMUSG00000020745 and 18472, nuclei, phosphoprotein binding, regulatory subunit 1 (45kDa), this GO :0000086 and G2/M transition of mitotic cell cycle and biological process this GO :0000132 and establishment of mitotic spindle orientation and biological process this GO :0000226 and microtubule cytoskeleton organization and biological process this GO :0000235 and astral microtubule and cellular component this GO :0000278 and mitotic cell cycle and biological process this GO :0000776 and kinetochore and cellular component this GO :0001667 and ameboidal cell migration and biological process this GO :0001675 and acrosome assembly and biological process this GO :0001764 and neuron migration and biological process this GO :0001961 and positive regulation of cytokine-mediated signaling pathway and biological process this GO :0005515 and protein binding and molecular function this GO :0005635 and nuclear envelope and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005871 and kinesin complex and cellular component this GO :0005875 and microtubule associated complex and cellular component this GO :0005938 and cell cortex and cellular component this GO :0007017 and microtubule-based process and biological process this GO :0007067 and mitotic nuclear division and biological process this GO :0007097 and nuclear migration and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007405 and neuroblast proliferation and biological process this GO :0007420 and brain development and biological process this GO :0007611 and learning or memory and biological process this GO :0008017 and microtubule binding and molecular function this GO :0008090 and retrograde axon car this GO transport and biological process this GO :0008152 and metabolic process and biological process this GO :0008201 and heparin binding and molecular function this GO :0008344 and adult locomotory behavior and biological process this GO :0009306 and protein secretion and biological process this GO :0010977 and negative regulation of neuron projection development and biological process this GO :0015630 and microtubule cytoskeleton and cellular component this GO :0016042 and lipid catabolic process and biological process this GO :0016477 and cell migration and biological process this GO :0016787 and hydrolase activity and molecular function this GO :0017145 and stem cell division and biological process this GO :0019226 and transmission of nerve impulse and biological process this GO :0021540 and corpus callosum morphogenesis and biological process this GO :0021766 and hippocampus development and biological process this GO :0021819 and layer formation in cerebral cortex and biological process this GO :0021895 and cerebral cortex neuron differentiation and biological process this GO :0021987 and cerebral cortex development and biological process this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030424 and axon and cellular component this GO :0030426 and growth cone and cellular component this GO :0031023 and microtubule organizing center organization and biological process this GO :0031252 and cell leading edge and cellular component this GO :0031512 and motile primary cilium and cellular component this GO :0031965 and nuclear membrane and cellular component this GO :0031982 and vesicle and cellular component this GO :0032319 and regulation of Rho GTPase activity and biological process this GO :0032403 and protein complex binding and molecular function this GO :0034452 and dynactin binding and molecular function this GO :0036035 and osteoclast development and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043005 and neuron projection and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043274 and phospholipase binding and molecular function this GO :0045502 and dynein binding and molecular function this GO :0045505 and dynein intermediate chain binding and molecular function this GO :0045773 and positive regulation of axon extension and biological process this GO :0045931 and positive regulation of mitotic cell cycle and biological process this GO :0046329 and negative regulation of JNK cascade and biological process this GO :0046469 and platelet activating factor metabolic process and biological process this GO :0047496 and vesicle transport along microtubule and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048854 and brain morphogenesis and biological process this GO :0050885 and neuromuscular process controlling balance and biological process this GO :0051081 and nuclear envelope disassembly and biological process this GO :0051219 and phosphoprotein binding and molecular function this GO :0051660 and establishment of centrosome localization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008017: microtubule binding and also this GO :0008201: heparin binding and also this GO :0016787: hydrolase activity and also this GO :0032403: protein complex binding and also this GO :0034452: dynactin binding and also this GO :0042803: protein homodimerization activity and also this GO :0043274: phospholipase binding and also this GO :0045502: dynein binding and also this GO :0045505: dynein intermediate chain binding and also this GO :0051219: phosphoprotein binding, this GO :0008017: microtubule binding, this GO :0008201: heparin binding, this GO :0016787: hydrolase activity, this GO :0032403: protein complex binding, this GO :0034452: dynactin binding, this GO :0042803: protein homodimerization activity, this GO :0043274: phospholipase binding, this GO :0045502: dynein binding, this GO :0045505: dynein intermediate chain binding, this GO :0051219: phosphoprotein binding, platelet-activating factor acetylhydrolase 1b |
| Identity | 8574 |
| Gene | PAFAH1B1 |
| Long gene name | platelet activating factor acetylhydrolase 1b regulatory subunit 1 |
| Synonyms gene | MDCR MDS |
| Synonyms gene name | alpha subunit (45kD) Miller-Dieker syndrome chromosome region platelet-activating factor acetylhydrolase, alpha subunit 45kDa platelet-activating factor acetylhydrolase, isoform Ib, isoform Ib, isoform Ib, platelet-activating factor acetylhydrolase, regulatory subunit 1 (45kDa) , subunit 1 (45kDa) platelet-activating factor acetylhydrolase 1b |
| Synonyms | LIS1 PAFAH NudF |
| Synonyms name | lissencephaly-1 |
| Locus | 17p13, 3 |
| Discovery year | 1998-04-03 |
| GenBank acession | L25107 |
| Entrez gene record | 5048 |
| Pubmed identfication | 8355785 9063735 |
| RefSeq identity | NM_000430 |
| Classification | WD repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000177574 |
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