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LMX1b/NPS1 Antibody, Cy7 Conjugated

LMX1b/NPS1 Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, LMX1b/NPS1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLMX1b/NPS1
SpecificityThis is a highly specific antibody against LMX1b/NPS1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human LMX1b/NPS1
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background In addition, LMX1B along with LIM1 control the initial trajectory of motor axons in the developing mammalian limb, LMX1B belongs to the LIM-homeodomain family, LMX1B directly regulates the coordinated expression of alpha 3(IV) and alpha 4(IV) collagen required for normal glomerular basement membrane (GBM) morphogenesis, LMX1B is also necessary for normal development of the eye and in regulating dopaminergic neurogenesis and may be involved in developmental glaucoma and the aetiology of idiopathic Parkinsonâ, NPS is caused by putative loss-of-function mutations in the transcription factor LMX1B, Specifically, Twenty-two novel mutations may occur in the gene encoding LMX1B and the type and distribution of the mutations support the hypothesis that NPS is the result of haploinsufficiency for LMX1B, and the dysregulation of LMX1B in GBM contributes to the renal pathology and nephrosis in NPS, frequently, members of which are known to be important for pattern formation during development, renal disease, skeletal anomalies and, &euro, &trade, Nail-patella syndrome (NPS) is an autosomal dominant disorder characterized by dyplasia of finger nails, s disease
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetLMX1b/NPS1 Conjugated
Short name Conjugated, LMX1b/NPS1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, LMX1b/NPS1 (Antibody to)
Alternative techniqueantibodies
Identity 6654
Gene LMX1B
Long gene name LIM homeobox transcription factor 1 beta
Synonyms gene NPS1
Synonyms gene name LIM homeobox transcription factor 1, beta
Locus 9q33, 3
Discovery year 1998-02-11
GenBank acession U77457
Entrez gene record 4010
Pubmed identfication 9441763 9590287
Classification LIM class homeoboxes
Havana BLAST/BLAT OTTHUMG00000020692
Locus Specific Databases LRG_1014

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