| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | LRP1 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | WB |
| Recommended dilutions | 5-1ug/ml, Western blot: 0 |
| Notes | Titration of the LRP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This LRP1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID # | 4035 |
| Purity | Antigen affinity |
| Description | In humans, It mediates the endocytosis and degradation of secreted amyloid precursor protein, It shows strong calcium binding, LRP1 has a role in macrophage migration and that it is critical for internalization of integrin alpha-M/beta-2, LRP1 is involved in several cellular processes, also called TGFBR5 and CD91, and clearance of apoptotic cells, including intracellular signaling, is a protein forming a receptor found in the plasma membrane of cells involved in receptor-mediated endocytosis, lipid homeostasis, suggesting that a single metabolic pathway links two molecules implicated in the pathophysiology of Alzheimer disease, the protein is encoded by the LRP1 gene, Low density lipoprotein receptor-related protein 1 |
| Immunogen | Human partial recombinant protein (AA 4351-4544) was used as the immunogen for this LRP1 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the LRP1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | LRP1 |
| Short name | LRP1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | low density lipoprotein receptor-related protein 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | A2MR and APOER and APR and CD91 and IGFBP3R and LRP and LRP1A and TGFBR5, LRP1 and IDBG-42176 and ENSG00000123384 and 4035, LRP1 and IDBG-635332 and ENSBTAG00000010830 and 533894, Lrp1 and IDBG-195360 and ENSMUSG00000040249 and 16971, lipoprotein particle receptor binding, nuclei, this GO :0001523 and retinoid metabolic process and biological process this GO :0002020 and protease binding and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005765 and lysosomal membrane and cellular component this GO :0005768 and endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005905 and coated pit and cellular component this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0007205 and protein kinase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0007568 and aging and biological process this GO :0007603 and phototransduction, this GO :0002020: protease binding, this GO :0002020: protease binding and also this GO :0004872: receptor activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0032403: protein complex binding and also this GO :0034185: apolipoprotein binding and also this GO :0042954: lipoprotein transporter activity and also this GO :0044822: poly(A) RNA binding and also this GO :0070325: lipoprotein particle receptor binding, this GO :0004872: receptor activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0032403: protein complex binding, this GO :0034185: apolipoprotein binding, this GO :0042954: lipoprotein transporter activity, this GO :0044822: poly(A) RNA binding, this GO :0070325: lipoprotein particle receptor binding, visible light and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0008283 and cell proliferation and biological process this GO :0010875 and positive regulation of cholesterol efflux and biological process this GO :0014912 and negative regulation of smooth muscle cell migration and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030136 and clathrin-coated vesicle and cellular component this GO :0030178 and negative regulation of Wnt signaling pathway and biological process this GO :0030425 and dendrite and cellular component this GO :0030666 and endocytic vesicle membrane and cellular component this GO :0032370 and positive regulation of lipid transport and biological process this GO :0032374 and regulation of cholesterol transport and biological process this GO :0032403 and protein complex binding and molecular function this GO :0032429 and regulation of phospholipase A2 activity and biological process this GO :0032956 and regulation of actin cytoskeleton organization and biological process this GO :0034185 and apolipoprotein binding and molecular function this GO :0035909 and aorta morphogenesis and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042953 and lipoprotein transport and biological process this GO :0042954 and lipoprotein transporter activity and molecular function this GO :0043025 and neuronal cell body and cellular component this GO :0043235 and receptor complex and cellular component this GO :0043277 and apoptotic cell clearance and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0051222 and positive regulation of protein transport and biological process this GO :0070325 and lipoprotein particle receptor binding and molecular function this GO :0097242 and beta-amyloid clearance and biological process this GO :2000587 and negative regulation of platelet-derived growth factor receptor-beta signaling pathway and biological process, low density lipoprotein receptor-related protein 1 |
| Identity | 29911 |
| Gene | C1D |
| Long gene name | C1D nuclear receptor corepressor |
| Synonyms gene name | C1D nuclear receptor co-repressor |
| Synonyms | SUNCOR SUN-CoR LRP1 Rrp47 |
| Synonyms name | small unique nuclear receptor co-repressor |
| Locus | 2p14 |
| Discovery year | 2009-02-06 |
| Entrez gene record | 10438 |
| Pubmed identfication | 9469821 17599775 17412707 11801738 9405624 |
| RefSeq identity | NM_006333 |
| Havana BLAST/BLAT | OTTHUMG00000129564 |
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