Name : LRRTM3 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN7283515073
| Long name | ALEXA FLUOR 488 Conjugated, LRRTM3 Polyclonal Antibody |
| Also known as | Anti-LRRTM3 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | LRRTM3 |
| Specificity | This is a highly specific antibody against LRRTM3 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LRRTM3 |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | All LRR repeats contain a variable segment and a highly conserved segment, As a result of alternative splicing events, Expressed in neuronal tissues, LRRTM family members are known to exhibit synaptogenic activity, LRRTM3 (leucine rich repeat transmembrane neuronal 3) is a 581 amino acid single-pass type I membrane protein belonging to the LRRTM family, LRRTM3 is encoded by a gene that maps to a region of chromosome 10 that has been linked to late-onset Alzheimer disease and elevated plasma Beta-Amyloid, LRRTM3 is involved in the development and maintenance of the vertebrate nervous system, Localizing predominantly to the nervous system, The LRRTM protein family plays a role in the regulation of various cellular events during nervous system development, allowing it to accommodate several leucine residues within a tightly packed core, and contains ten LRR repeats, the latter of which accounts for 11 or 12 residues of the entire LRR motif, two LRRTM3 isoforms exist, The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the LRRTM3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | LRRTM3 |
| Short name | LRRTM3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, LRRTM3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 19410 |
| Gene | LRRTM3 |
| Long gene name | leucine rich repeat transmembrane neuronal 3 |
| Locus | 10q21, 3 |
| Discovery year | 2004-02-04 |
| GenBank acession | BX640611 |
| Entrez gene record | 347731 |
| Pubmed identfication | 12676565 |
| RefSeq identity | NM_178011 |
| Havana BLAST/BLAT | OTTHUMG00000018332 |