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LTBR Antibody

LTBR Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenLTBR
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the LTBR antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis LTBR antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P36941
PurityAntigen affinity
Description By linkage analysis with recombinant inbred mouse strains, Lo et al, Nakamura et al, Presumably, Silva-Santos et al, also called TNFCR or LT-BETA-R, as critical regulators of key enzymes that control lipid metabolism, is a receptor for lymphotoxin which in humans is encoded by the LTBR gene, the human homolog is located on 12p13, tumor necrosis factor cytokine family members that are primarily expressed on lymphocytes, (1995) demonstrated that the Tnfcr locus is close to the Tnfr1 gene on mouse chromosome 6, (2005) reported that double-positive T cells regulate the differentiation of early thymocyte progenitors and gamma-delta cells by a mechanism dependent on the transcription factor ROR-gamma-t and LTBR, (2007) identified lymphotoxin and LIGHT (TNFSF14), Lymphotoxin B Receptor
ImmunogenAn amino acid sequence from the C-terminus of human Lymphotoxin B Receptor (ATPSNRGPRNQFITHD) was used as the immunogen for this LTBR antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the LTBR antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetLTBR
Short nameLTBR Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name member 3) (Antibody to), lymphotoxin b receptor (TNFR superfamily
Alternative techniqueantibodies
Alternative to gene target CD18 and D12S370 and LT-BETA-R and TNF-R-III and TNFCR and TNFR-RP and TNFR2-RP and TNFR3 and TNFRSF3, LTBR and IDBG-13973 and ENSG00000111321 and 102724071, LTBR and IDBG-640501 and ENSBTAG00000015312 and 504653, Ltbr and IDBG-189788 and ENSMUSG00000030339 and 17000, Plasma membranes, identical protein binding, member 3), this GO :0005515 and protein binding and molecular function this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0042802 and identical protein binding and molecular function this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0042802: identical protein binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0042802: identical protein binding, 4055, lymphotoxin beta receptor (TNFR superfamily
Identity 6718
Gene LTBR
Long gene name lymphotoxin beta receptor
Synonyms gene D12S370
Synonyms TNFCR TNFR-RP TNFR2-RP TNF-R-III TNFRSF3
Synonyms name TNFR superfamily, member 3
Locus 12p13
Discovery year 1996-03-12
GenBank acession L04270
Entrez gene record 4055
Pubmed identfication 8171323 8486360
Classification Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT OTTHUMG00000168356

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