Name : LYK5 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN4152991635
| Long name | LYK5 Primary Polyclonal Antibody |
| Also known as | LYK5 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | LYK5 |
| Specificity | This is a highly specific antibody against LYK5 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LYK5 |
| Gene ID number | 92335 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm, It specifically binds LKB1 and plays a key role in regulating the tumor suppressor activities of LKB1, LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity, LYK5-LKB1 interaction results in phosphorylation of LYK5 and enhanced autophosphorylation of LKB1, Members of the STE-20 like kinase family are known to stimulate MAPK pathways by directly activating MAPKKK |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Protein kinase LYK5, STE20 related adapter protein, STRAA_HUMAN, STRAD, STRAD alpha, Serologically defined breast cancer antigen NY BR 96 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | LYK5 |
| Short name | LYK5 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | LYK5 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 30172 |
| Gene | STRADA |
| Long gene name | STE20-related kinase adaptor alpha |
| Synonyms | NY-BR-96 LYK5 Stlk STRAD |
| Synonyms name | STE20-like pseudokinase |
| Locus | 17q23, 3 |
| Discovery year | 2008-09-15 |
| GenBank acession | AF308302 |
| Entrez gene record | 92335 |
| Pubmed identfication | 12805220 17921699 |
| Havana BLAST/BLAT | OTTHUMG00000178908 |