| Long name | LRR and PYD domains-containing protein 3 (NLRP3), partial, Recombinant Macaca mulatta (Rhesus macaque) NACHT |
| Alternative names | LRR and PYD domains-containing protein 3, LRR and PYD domains-containing protein 3, LRR and PYD domains-containing protein 3, NACHT, NACHT, NLR family pyrin domain containing 3, NACHT |
| Gene name | N/A |
| Other gene names | NLRP3, NLRP3 |
| General description | All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, LRR and PYD domains-containing protein 3 (NLRP3), The protein can be with or without a His-Tag or other tag in accordance to customer's request, coli, partial is a recombinant protein expressed in E, (Rhesus macaque) NACHT |
| Product category | Recombinant Proteins |
| Expression system | coli, E |
| Available also expressed in: | Yeast, E Coli |
| Purity | Greater than 90% (determined by SDS-PAGE) |
| Form | We can custom produce according to your specifications, This item requires custom production and lead time is between 5-9 weeks |
| Storage | Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications | IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| About | Monkeys like rhesus's or the rhesus macaque (Macaca mulatta) are the most used apes in laboraty models |
| Gene target | LRR PYD domains protein 3 (NLRP3) partial, Macaca mulatta macaque) NACHT |
| Short name | LRR PYD domains-containing protein 3 (NLRP3) partial, Macaca mulatta ( macaque) NACHT |
| Species | Rhesuses, Rhesus |
| Alternative name | LRR and PYD domains-containing protein 3 (NLR family, partial, pyrin domain containing 3), Macaca mulatta (Rhesus macaque) NACHT |
| Alternative to gene target | Cytoplasm, NLRP3 and IDBG-107914 and ENSG00000162711 and 114548, NLRP3 and IDBG-645402 and ENSBTAG00000001273 and 538639, Nlrp3 and IDBG-178924 and ENSMUSG00000032691 and 216799, leucine rich repeat containing receptor signaling pathway and biological process this GO :0042347 and negative regulation of NF-kappaB import into nucleus and biological process this GO :0042834 and peptidoglycan binding and molecular function this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0044546 and NLRP3 inflammasome complex assembly and biological process this GO :0045087 and innate immune response and biological process this GO :0050701 and interleukin-1 secretion and biological process this GO :0050713 and negative regulation of interleukin-1 beta secretion and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051259 and protein oli this GO merization and biological process this GO :0051607 and defense response to virus and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0072559 and NLRP3 inflammasome complex and cellular component, peptidoglycan binding, pyrin domain containing 3, this GO :0002674 and negative regulation of acute inflammatory response and biological process this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0006952 and defense response and biological process this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0009595 and detection of biotic stimulus and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032611 and interleukin-1 beta production and biological process this GO :0032621 and interleukin-18 production and biological process this GO :0035872 and nucleotide-binding domain, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0042834: peptidoglycan binding, this GO :0005524: ATP binding, this GO :0042834: peptidoglycan binding, NLR family |
| Identity | 16400 |
| Gene | NLRP3 |
| Long gene name | NLR family pyrin domain containing 3 |
| Synonyms gene | C1orf7 CIAS1 |
| Synonyms gene name | cold autoinflammatory syndrome 1 |
| Synonyms | AGTAVPRL AII AVP FCAS FCU NALP3 PYPAF1 MWS CLR1, 1 |
| Synonyms name | Cryopyrin nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3 |
| Locus | 1q44 |
| Discovery year | 2001-08-28 |
| GenBank acession | AF054176 |
| Entrez gene record | 114548 |
| Pubmed identfication | 10741953 |
| RefSeq identity | NM_004895 |
| Classification | NLR family Pyrin domain containing |
| Havana BLAST/BLAT | OTTHUMG00000040647 |
| Locus Specific Databases | INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations LRG_197 |