| Also known as | MAGE-1 |
| Other names | 1 (directs expression of antigen MZ2-E), Antigen MZ2-E, CT1, Cancer/testis antigen 1, MAGE-1 antigen, MAGE-1 antigen, Melanoma-associated antigen 1, antigen MZ2-E, cancer/testis antigen 1, cancer/testis antigen family 1, melanoma antigen MAGE-1, melanoma antigen family A, melanoma antigen family A 1, melanoma-associated antigen 1, melanoma-associated antigen MZ2-E, member 1, 1, 1, 1, melanoma-associated antigen 1 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | MAGEA1 |
| Gene name synonims | N/A |
| Other gene names | CT1, CT1, MAGE1, MAGE1, MAGE1A, MAGEA1, 1, 1, MAGEA1 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | kappa, IgG1 |
| Clone | MA454 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Dog, Due to limited knowledge and inability for testing each and every species, Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | -10, -4, -3, -6 -9, -or -12 protein, Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, CD8+ T lymphocyte clones (CTL), Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs), Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The MAGE family of genes codes an important group of antigens, This MAb does not cross-react with MAGE-2, This particular antibody might cross react with speacies outside of the listed ones, brain tumors of glial origin, breast, colorectal, cytolytic, gastric, identified as MAGE-1, neuroblastoma, non-small cell lung cancer, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy, tumor directed and specific, Recognizes a protein of 42-46kDa |
| Purification method | N/A |
| Form/Appearance | N/A |
| Concentration | N/A |
| Storage and shipping | Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications: | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA) |
| Gene target | MAGE-1 |
| Short name | MAGE-1 |
| Alternative name | MAGE-1 |
| Identity | 6796 |
| Gene | MAGEA1 |
| Long gene name | MAGE family member A1 |
| Synonyms gene | MAGE1 |
| Synonyms gene name | 1 (directs expression of antigen MZ2-E) melanoma antigen family A1 , melanoma antigen family A |
| Synonyms | MGC9326 CT1, 1 |
| Synonyms name | melanoma-associated antigen 1 melanoma-associated antigen MZ2-E melanoma antigen MAGE-1 melanoma antigen family A 1 cancer/testis antigen family 1, member 1 |
| Locus | Xq28 |
| Discovery year | 1994-04-04 |
| Entrez gene record | 4100 |
| Pubmed identfication | 1840703 |
| RefSeq identity | NM_004988 |
| Classification | MAGE family |
| Havana BLAST/BLAT | OTTHUMG00000024192 |
| Locus Specific Databases | Mental Retardation database |
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