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MARCH3 Antibody, Biotin Conjugated

MARCH3 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, MARCH3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target Antigen37681
SpecificityThis is a highly specific antibody against 37681
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human MARCH3
Gene ID number115123
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Involved in the pathway of protein modification, MARCH3 (membrane-associated ring finger (C3HC4) 3), MARCH3 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and is thought to be involved in endosomal trafficking events, The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), also known as RNF173, is a 253 amino acid multi-pass membrane protein that localizes to cytoplasmic vesicles and early endosomes and contains one RING-CH-type zinc finger, the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s), Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms MGC48332 MARCH-III RNF173
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMARCH3 Conjugated
Short name Conjugated, MARCH3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name E3 ubiquitin protein ligase (Antibody to), biotinilated coupled, membrane-associated ring finger (C3HC4) 3
Alternative techniqueantibodies
Alternative to gene target E3 ubiquitin protein ligase, MARCH3 and IDBG-39523 and ENSG00000173926 and 115123, MARCH3 and IDBG-644898 and ENSBTAG00000006797 and 520348, March3 and IDBG-148017 and ENSMUSG00000032656 and 320253, Plasma membranes, metal ion binding, this GO :0005515 and protein binding and molecular function this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0006897 and endocytosis and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0031901 and early endosome membrane and cellular component this GO :0046872 and metal ion binding and molecular function, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0016874: ligase activity and also this GO :0046872: metal ion binding, this GO :0008270: zinc ion binding, this GO :0016874: ligase activity, this GO :0046872: metal ion binding, membrane-associated ring finger (C3HC4) 3
Identity 28728
Gene MARCH3
Long gene name membrane associated ring-CH-type finger 3
Synonyms gene name E3 ubiquitin protein ligase , membrane-associated ring finger (C3HC4) 3 membrane-associated ring finger (C3HC4) 3
Locus 5q23, 2
Discovery year 2005-01-26
GenBank acession AF055007
Entrez gene record 115123
Pubmed identfication 14722266 8619474
RefSeq identity NM_178450
Classification Membrane associated ring-CH-type fingers Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000128968

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