Name : MARCO Antibody
Supplier : NJS POLY
Price :199
SKU : GEN4470907715
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | MARCO |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, FACS, IHC, WB |
| Recommended dilutions | Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes | Titration of the MARCO antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This MARCO antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q9UEW3 |
| Purity | Antigen affinity |
| Description | C-terminal, In addition to short cytoplasmic and transmembrane domains, The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains, extracellular collagenous domain, scavenger receptor cysteine-rich (SRCR) domain, there is an extracellular spacer domain and a long, MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system |
| Immunogen | A portion of amino acids 13-40 from the human protein was used as the immunogen for this MARCO antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the MARCO antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | MARCO |
| Short name | MARCO Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | macrophage receptor including collagenous structure (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | MARCO and IDBG-642407 and ENSBTAG00000018473 and, MARCO and IDBG-67847 and ENSG00000019169 and 8685, Marco and IDBG-188086 and ENSMUSG00000026390 and 17167, Plasma membranes, SCARA2, signaling pattern recognition receptor activity, this GO :0002221 and pattern recognition receptor signaling pathway and biological process this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005044 and scavenger receptor activity and molecular function this GO :0005581 and collagen trimer and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006897 and endocytosis and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0008329 and signaling pattern recognition receptor activity and molecular function this GO :0016020 and membrane and cellular component this GO :0030666 and endocytic vesicle membrane and cellular component this GO :0043277 and apoptotic cell clearance and biological process this GO :0045087 and innate immune response and biological process, this GO :0004888: transmembrane signaling receptor activity, this GO :0004888: transmembrane signaling receptor activity and also this GO :0005044: scavenger receptor activity and also this GO :0008329: signaling pattern recognition receptor activity, this GO :0005044: scavenger receptor activity, this GO :0008329: signaling pattern recognition receptor activity, macrophage receptor with collagenous structure |
| Identity | 6895 |
| Gene | MARCO |
| Long gene name | macrophage receptor with collagenous structure |
| Synonyms | SCARA2 |
| Synonyms name | member 2 , scavenger receptor class A |
| Locus | 2q14, 2 |
| Discovery year | 1998-11-26 |
| GenBank acession | AF035819 |
| Entrez gene record | 8685 |
| Pubmed identfication | 9468508 7867067 10331948 |
| RefSeq identity | NM_006770 |
| Classification | Scavenger receptors |
| Havana BLAST/BLAT | OTTHUMG00000131400 |