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MARCO Antibody

MARCO Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenMARCO
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IHC, WB
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the MARCO antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis MARCO antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9UEW3
PurityAntigen affinity
Description C-terminal, In addition to short cytoplasmic and transmembrane domains, The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains, extracellular collagenous domain, scavenger receptor cysteine-rich (SRCR) domain, there is an extracellular spacer domain and a long, MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system
ImmunogenA portion of amino acids 13-40 from the human protein was used as the immunogen for this MARCO antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the MARCO antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetMARCO
Short nameMARCO Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namemacrophage receptor including collagenous structure (Antibody to)
Alternative techniqueantibodies
Alternative to gene target MARCO and IDBG-642407 and ENSBTAG00000018473 and, MARCO and IDBG-67847 and ENSG00000019169 and 8685, Marco and IDBG-188086 and ENSMUSG00000026390 and 17167, Plasma membranes, SCARA2, signaling pattern recognition receptor activity, this GO :0002221 and pattern recognition receptor signaling pathway and biological process this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005044 and scavenger receptor activity and molecular function this GO :0005581 and collagen trimer and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006897 and endocytosis and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0008329 and signaling pattern recognition receptor activity and molecular function this GO :0016020 and membrane and cellular component this GO :0030666 and endocytic vesicle membrane and cellular component this GO :0043277 and apoptotic cell clearance and biological process this GO :0045087 and innate immune response and biological process, this GO :0004888: transmembrane signaling receptor activity, this GO :0004888: transmembrane signaling receptor activity and also this GO :0005044: scavenger receptor activity and also this GO :0008329: signaling pattern recognition receptor activity, this GO :0005044: scavenger receptor activity, this GO :0008329: signaling pattern recognition receptor activity, macrophage receptor with collagenous structure
Identity 6895
Gene MARCO
Long gene name macrophage receptor with collagenous structure
Synonyms SCARA2
Synonyms name member 2 , scavenger receptor class A
Locus 2q14, 2
Discovery year 1998-11-26
GenBank acession AF035819
Entrez gene record 8685
Pubmed identfication 9468508 7867067 10331948
RefSeq identity NM_006770
Classification Scavenger receptors
Havana BLAST/BLAT OTTHUMG00000131400

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