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MASP Antibody

MASP Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMASP Primary Polyclonal Antibody
Also known asMASP PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMASP
SpecificityThis is a highly specific antibody against MASP
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range130-180/488
Subcellular locationSecreted
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MASP
Gene ID number5648
Swiss ProtP48740
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction, Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5, The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them, Functions in the lectin pathway of complement
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CRARF, CRARF1, Complement factor MASP-3, Complement-activating component of Ra-reactive factor, MAP1, MASP, MASP-1, MASP1, MASP3, MAp44, Mannan-binding lectin serine protease 1, Mannose-binding lectin-associated serine protease 1, Mannose-binding protein-associated serine protease, PRSS5, Ra-reactive factor serine protease p100, RaRF, Serine protease 5, 3MC1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMASP
Short nameMASP Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMASP (Antibody to)
Alternative techniqueantibodies
Identity 6901
Gene MASP1
Long gene name mannan binding lectin serine peptidase 1
Synonyms gene CRARF PRSS5
Synonyms gene name mannan-binding lectin serine protease 1 (C4/C2 activating component of Ra-reactive factor) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
Synonyms MASP
Synonyms name C4/C2 activating component of Ra-reactive factor
Locus 3q27, 3
Discovery year 1995-07-06
GenBank acession D28593
Entrez gene record 5648
Pubmed identfication 8018603 8240317
RefSeq identity NM_001879
Classification Sushi domain containing Proteases, serine
Havana BLAST/BLAT OTTHUMG00000156461
Locus Specific Databases LRG_349

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