MB21D1 (1697CT136.65.30) Monoclonal Antibody

MB21D1 (1697CT136.65.30) Monoclonal Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 281

Size 0.1ml

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Long name	30) Monoclonal Antibody, 65, MB21D1 (1697CT136
Also known as	30) Monoclonal Antibody, 65, MB21D1 (1697CT136
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	MB21D1
Specificity	This is a highly specific antibody against MB21D1
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Monoclonal
Clone number	1697CT136, 30, 65
Source	This MB21D1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1-185 amino acids from human MB21D1
Gene ID number	115004
Swiss Prot	Q8N884
Tested Applications	WB
Recommended dilutions	WB(1:4000)
Cross reactivity	Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Binds cytosolic DNA directly, Catalysis involves both the formation of a 2', Has antiviral activity by acting as a key cytosolic DNA sensor, a second messenger that binds to and activates TMEM173/STING, cGAMP can be transferred between cells by virtue of packaging within viral particles contributing to IFN-induction in newly infected cells in a cGAS-independent but TMEM173/STING-dependent manner (PubMed:26229115), leading to activation and synthesis of cGAMP, producing c[G(2', the presence of double-stranded DNA (dsDNA) in the cytoplasm being a danger signal that triggers the immune responses, thereby triggering type-I interferon production, 5' phosphodiester linkage at the ApG step, 5' phosphodiester linkage at the GpA step and the formation of a 3', 5')pA(3', 5')p], Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	2'3'-cGAMP synthase, C6orf150, Cyclic GMP-AMP synthase, MB21D1, Mab-21 domain-containing protein 1, cGAMP synthase, h-cGAS, cGAS
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About	Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target	30) Monoclonal, 65, MB21D1 (1697CT136
Short name	30) Monoclonal Antibody, 65, MB21D1 (1697CT136
Technique	Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name	30) monoclonal (Antibody to), 65, MB21D1 (1697CT136
Alternative technique	antibodies
Identity	21367
Gene	MB21D1
Long gene name	Mab-21 domain containing 1
Synonyms gene	C6orf150
Synonyms gene name	chromosome 6 open reading frame 150
Synonyms	cGAS
Synonyms name	cyclic GMP-AMP synthase
Locus	6q13
Discovery year	2003-06-10
GenBank acession	BC012928
Entrez gene record	115004
RefSeq identity	NM_138441
Havana BLAST/BLAT	OTTHUMG00000015034

MB21D1 (1697CT136.65.30) Monoclonal Antibody

MB21D1 (1697CT136.65.30) Monoclonal Antibody size: 0.1ml 281

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