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MCAM(Tyr641) Antibody

MCAM(Tyr641) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMCAM(Tyr641) Primary Polyclonal Antibody
Also known asMCAM(Tyr641) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMCAM Tyr641
SpecificityThis is a highly specific antibody against MCAM Tyr641
Modification(s)Phosphorylation
Modification site(s)Tyr641
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human MCAM around the phosphorylation site of Tyr641
Gene ID number4162
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, Could be an adhesion molecule active in neural crest cells during embryonic development, Its expression may allow melanoma cells to interact with cellular elements of the vascular system, and a transient increase in the intracellular calcium concentration, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue, thereby enhancing hematogeneous tumor spread, Plays a role in cell adhesion
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Cell surface glycoprotein P1H12, MCAM, MUC18, Melanoma cell adhesion molecule, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen, Cell surface glycoprotein MUC18
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMCAM(Tyr641)
Short nameMCAM(Tyr641) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namemelanoma cell adhesion molecule(Tyr641) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CD146 and MUC18, MCAM and IDBG-631776 and ENSBTAG00000006835 and 281301, MCAM and IDBG-74428 and ENSG00000076706 and 102465453, Mcam and IDBG-155835 and ENSMUSG00000032135 and 84004, nuclei, protein binding, this GO :0003094 and glomerular filtration and biological process this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030335 and positive regulation of cell migration and biological process this GO :0061042 and vascular wound healing and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, 4162, melanoma cell adhesion molecule
Identity 6934
Gene MCAM
Long gene name melanoma cell adhesion molecule
Synonyms MUC18 CD146
Synonyms name Gicerin
Locus 11q23, 3
Discovery year 1995-12-18
GenBank acession X68264
Entrez gene record 4162
Pubmed identfication 2602381 10702685
Classification C2-set domain containing CD molecules V-set domain containing Immunoglobulin like domain containing
Havana BLAST/BLAT OTTHUMG00000166197

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