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MCM4 Antibody

MCM4 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenMCM4
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC, WB
Recommended dilutionsIHC (Paraffin): 1:10-1:50, Western blot: 1:1000
NotesTitration of the MCM4 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis MCM4 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P33991
PurityAntigen affinity
Description 6 and 7 proteins possesses DNA helicase activity, Alternatively spliced transcript variants encoding the same protein have been reported, The MCM complex consisting of this protein and MCM2, The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins, The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex, This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks, and may act as a DNA unwinding enzyme, The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication
ImmunogenA portion of amino acids 637-665 from the human protein was used as the immunogen for this MCM4 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the MCM4 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetMCM4
Short nameMCM4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMCM4 (Antibody to)
Alternative techniqueantibodies
Identity 6947
Gene MCM4
Long gene name minichromosome maintenance complex component 4
Synonyms gene CDC21
Synonyms gene name MCM4 minichromosome maintenance deficient 4 (S, cerevisiae)
Synonyms CDC54 hCdc21 P1-Cdc21 MGC33310
Locus 8q11, 21
Discovery year 1994-12-13
Entrez gene record 4173
Pubmed identfication 7601140
RefSeq identity NM_005914
Classification MCM family
Havana BLAST/BLAT OTTHUMG00000164205

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