Filters

MeCP2 Antibody

MeCP2 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenMeCP2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IHC, WB
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the MeCP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis MeCP2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P51608
PurityAntigen affinity
Description Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, It can bind specifically to a single methyl-CpG pair, It is not influenced by sequences flanking the methyl-CpGs, Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A, [UniProt], with a preference for 5-methylcytosine (5mC), MeCP2 is a chromosomal protein that binds to methylated DNA
ImmunogenA portion of amino acids 58-87 from the human protein was used as the immunogen for this MeCP2 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the MeCP2 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetMeCP2
Short nameMeCP2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMeCP2 (Antibody to)
Alternative techniqueantibodies
Identity 10470
Gene RTT
Long gene name methyl-CpG binding protein 2
Synonyms gene MRX16 MRX79
Synonyms gene name X-linked 16 mental retardation, X-linked 79 Rett syndrome methyl CpG binding protein 2 (Rett syndrome) methyl CpG binding protein 2 , mental retardation
Synonyms MECP2
Locus Xq28
Discovery year 1996-09-03
GenBank acession AF158180
Entrez gene record 4204
Pubmed identfication 1606614 10508514
RefSeq identity NM_004992
Classification X-linked mental retardation Methyl-CpG binding domain containing
Havana BLAST/BLAT OTTHUMG00000024229
Locus Specific Databases RettBASE Mental Retardation database LRG_764

Similar products

Subscribe to our Newsletter