Name : MFN2 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN4247511401
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | MFN2 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, FACS, IHC, WB |
| Recommended dilutions | Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes | Titration of the MFN2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This MFN2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | O95140 |
| Purity | Antigen affinity |
| Description | Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, This protein is involved in the regulation of vascular smooth muscle cell proliferation, and hereditary motor and sensory neuropathy VI, and it may play a role in the pathophysiology of obesity, which are both disorders of the peripheral nervous system, MFN2 is a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network |
| Immunogen | A portion of amino acids 447-476 from the human protein was used as the immunogen for this MFN2 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the MFN2 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | MFN2 |
| Short name | MFN2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | MFN2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 16877 |
| Gene | MFN2 |
| Long gene name | mitofusin 2 |
| Synonyms | CPRP1 KIAA0214 MARF CMT2A2 |
| Locus | 1p36, 22 |
| Discovery year | 2003-02-25 |
| GenBank acession | AF036536 |
| Entrez gene record | 9927 |
| Pubmed identfication | 12499352 11181170 |
| RefSeq identity | NM_014874 |
| Havana BLAST/BLAT | OTTHUMG00000002392 |
| Locus Specific Databases | Inherited Peripheral Neuropathies Mutation Database LRG_255 |